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Cordyceps sinensis composition for preventing or treating respiratory diseases and application thereof

A technology of Cordyceps spp

Inactive Publication Date: 2017-10-13
INST OF BOTANY JIANGSU PROVINCE & CHINESE ACADEMY OF SCI +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, respiratory diseases involve various white blood cells, cytokines and inflammatory mediators, so it is difficult for artificially cultivated Cordyceps militaris and Silkworm fungus to achieve extensive preventive and therapeutic effects on the respiratory system with only a single raw material

Method used

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  • Cordyceps sinensis composition for preventing or treating respiratory diseases and application thereof
  • Cordyceps sinensis composition for preventing or treating respiratory diseases and application thereof
  • Cordyceps sinensis composition for preventing or treating respiratory diseases and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] Get 500 kilograms of Cordyceps militaris, 300 kilograms of silkworm caterpillar fungus, 5 kilograms of arginine, pulverize through pulverizer respectively and obtain their powder, and order number is controlled at 80 orders. Mix the above-mentioned powdery Cordyceps militaris, Cordyceps militaris and arginine, stir well and evenly, and finally prepare the mixture to obtain the Chinese patent medicine of tablet, capsule, granule, electuary or powder.

Embodiment 2

[0022] Get 100 kilograms of Cordyceps militaris, 700 kilograms of silkworm caterpillar fungus, 5 kilograms of arginine, pulverize through pulverizer respectively and obtain their powder, and order number is controlled at 20 orders. Mix the above-mentioned powdery Cordyceps militaris, Cordyceps militaris and arginine, stir well and evenly, and finally prepare the mixture to obtain the Chinese patent medicine of tablet, capsule, granule, electuary or powder.

Embodiment 3

[0023] Example 3 Effects of Different Formulas on the Activity of Relieving Cough and Resolving Phlegm

[0024] Sample preparation: sample 1: this product (prepared according to the method of Example 1); sample 2: silkworm caterpillar fungus; sample 3: cordyceps militaris; sample 4: cordyceps sinensis;

[0025] Animal experiment method:

[0026] The effect on mice with cough induced by ammonia water was used to induce cough with ammonia water in mice. A batch of Kunming mice with a body weight of 18-22 g were screened by the method of ammonia water induced cough in the preliminary experiment. Mice that did not cough within 3 minutes were not selected. After the mice were stabilized for 2 days, get 60 qualified mice, half male and half male, and divide them into 6 groups at random according to body weight, control group (normal saline), Nian Ji'm Mi Lian Chuan Bei Pi Pa Kou group (10g / kg), each sample Group (0.6g crude drug / kg·bw), continuous administration for 7 days, the mic...

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Abstract

The invention belongs to the field of traditional Chinese medicines and discloses a silkworm-cultured cordyceps militaris composition for preventing or treating respiratory disease and application of the silkworm-cultured cordyceps militaris composition. The silkworm-cultured cordyceps militaris composition for preventing or treating respiratory disease is mainly prepared from the following components in parts by weight: 30-70 parts of silkworm-cultured cordyceps militaris, 10-50 parts of cordyceps militaris, and 0.1-10 parts of arginine. A Chinese patent medicine prepared from the composition for preventing and treating the respiratory disease has excellent 5-lipoxygenase inhibitory activity, airway inhibitory activity, airway inflammation inhibitory effect, ear swelling antiphlogistic effect, and cough-relieving and phlegm-eliminating activities, and can be used for effectively preventing or treating respiratory organ diseases such as asthma, chronic obstructive pulmonary disease, acute and chronic bronchitis, anaphylactic rhinitis, cough, excessive phlegm, acute lower respiratory infection (bronchitis and capillary bronchitis), pharyngitis, amygdalitis, laryngitis and acute upper respiratory infection.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine, and relates to a silkworm cordyceps composition for preventing or treating respiratory diseases and its application. Background technique [0002] Respiratory system disease is a common and frequently-occurring disease. The main lesions are in the trachea, bronchi, lungs and chest cavity. Mild cases often cause coughing, chest pain, and respiratory obstruction. Severe cases have dyspnea, leading to hypoxia or even respiratory failure and death. Due to air pollution, smoking, population aging and other factors, the incidence and mortality of diseases such as chronic obstructive pulmonary disease, bronchial asthma, lung cancer, pulmonary diffuse interstitial fibrosis and pulmonary infection have increased at home and abroad. reduce. [0003] Cordyceps sinensis (Berk.) Sacc.] is one of the "Three Treasures" in my country's medical treasure house, wild ginseng and velvet antler. It enjoys...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/068A61P11/00A61P11/06A61P11/02A61P37/08A61P11/14A61P11/10A61P11/04A61K31/198
CPCA61K9/14A61K31/198A61K36/068A61K2300/00
Inventor 韦敏吕晔郑生智邵世海
Owner INST OF BOTANY JIANGSU PROVINCE & CHINESE ACADEMY OF SCI
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