Unlock instant, AI-driven research and patent intelligence for your innovation.

A kind of midanacine-containing pharmaceutical composition

A midanacin and composition technology, which is applied in the field of midanacin pharmaceutical compositions and their preparation, can solve the problems of poor particle fluidity, low release rate, poor stability and the like, and achieves solutions to large-scale industrial production, Good dissolution and stability

Active Publication Date: 2018-01-19
KUNMING JIDA PHARMA
View PDF7 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0009] The conventional preparation method in the prior art prepares the new preparation of midana. Due to the physical and chemical properties of the new material of midana, it is easy to cause the particles in the prepared tablet to have poor fluidity, stickiness, poor stability, low release rate, complicated process, and production. High cost, difficult to achieve industrialized mass production
[0010] In order to improve product quality and overcome the problem of incapable of industrialized production, we have carried out a lot of design and research on technical solutions, selected the optimal prescription and process, and solved the above technical defects

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • A kind of midanacine-containing pharmaceutical composition
  • A kind of midanacine-containing pharmaceutical composition
  • A kind of midanacine-containing pharmaceutical composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0073] (1) Prescription

[0074] Midanacin 0.1g

[0075] Microcrystalline Cellulose 65g

[0076] Pregelatinized starch 70g

[0077] Magnesium Stearate 0.9g

[0078] Coating agent 4g

[0079] 50% ethanol aqueous solution appropriate amount

[0080] Make 1000 pieces

[0081] (2) Preparation method

[0082] 1) Preparation and processing of raw and auxiliary materials: pass Midanacin and other auxiliary materials through an 80-mesh sieve for use;

[0083] 2) Weighing and mixing: According to the prescription amount, the above-mentioned raw and auxiliary materials are respectively weighed and calculated by double check and calculation;

[0084] 3) Mixing: Mix the prescribed amount of midanacin first with the prescribed amount of pregelatinized starch, and then mix it with the prescribed amount of microcrystalline cellulose to make it fully mixed;

[0085] 4) Granulation: Add 50% ethanol aqueous solution to the mixed material to obtain a soft material with suitable hardness,...

Embodiment 2

[0094] (1) Prescription

[0095] Midanacin 0.1g

[0096] Microcrystalline Cellulose 95g

[0097] Pregelatinized starch 40g

[0098] Magnesium Stearate 0.9g

[0099] Coating agent 4g

[0100] 50% ethanol aqueous solution appropriate amount

[0101] Make 1000 pieces

[0102] (2) The preparation method is the same as in Example 1.

Embodiment 3

[0104] (1) Prescription

[0105] Midanacin 0.1g

[0106] Microcrystalline Cellulose 81g

[0107] Pregelatinized starch 54g

[0108] Magnesium Stearate 0.9g

[0109] Coating agent 4g

[0110] 50% ethanol aqueous solution appropriate amount

[0111] Make 1000 pieces

[0112] (2) The preparation method is the same as in Example 1.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
particle diameteraaaaaaaaaa
Login to View More

Abstract

The invention relates to a pharmaceutical composition containing imidafenacin and a preparation method of the pharmaceutical composition. Imidafenacin is mixed with pregelatinized starch and microcrystalline cellulose according to a certain ratio. The composition obtained by the invention is simple in prescription, mature in preparation process and good in dissolution effect.

Description

technical field [0001] The invention belongs to the technical field of pharmaceutical preparations, and in particular relates to a midanacin pharmaceutical composition and a preparation method thereof. Background technique [0002] Overactive bladder (OAB) is a common disorder characterized by urgency, with or without urge incontinence, often accompanied by frequent urination and nocturia. The symptoms of OAB are caused by involuntary contraction of the detrusor muscle during bladder filling. The etiology of OAB is still unclear. It may be caused by damage to the central inhibitory efferent pathways, peripheral sensory afferent pathways, or the bladder muscle itself. . [0003] There are about 50 to 100 million people in the world with the disease. There are slightly more women than men, and the incidence increases with age. At present, the drugs used for clinical treatment mainly include anticholinergic drugs, adrenergic receptor agonists, neurosensory afferent blockers,...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/30A61K31/4174A61K47/38A61K47/36A61P13/10
Inventor 严洁李轩
Owner KUNMING JIDA PHARMA
Features
  • R&D
  • Intellectual Property
  • Life Sciences
  • Materials
  • Tech Scout
Why Patsnap Eureka
  • Unparalleled Data Quality
  • Higher Quality Content
  • 60% Fewer Hallucinations
Social media
Patsnap Eureka Blog
Learn More

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2025 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com