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Traditional Chinese medicine composition for preventing and treating bovine uterine involution and its preparation method

A technology of uterine involution and composition, applied in the directions of drug combination, drug delivery, and pharmaceutical formulation, can solve the problems of increasing uterine burden, causing drug resistance of pathogenic bacteria, increasing uterine contractility and uterine tissue degradation rate, etc.

Active Publication Date: 2017-09-26
QINGDAO AGRI UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The above methods mostly use the method of injecting antibiotics and antiseptics into the uterus of cattle to prevent incomplete involution of the uterus of cattle, and it is difficult to effectively prevent incomplete involution of the uterus of cattle
This is because uterine involution depends on uterine contractility and the degradation rate of uterine tissue, and the artificial exclusion of lochia and the above-mentioned injection methods cannot increase uterine contraction force and the degradation rate of uterine tissue. The burden of the uterus is therefore not conducive to involution
In addition, the use of antibiotics will lead to drug resistance of pathogenic bacteria, and the quality of milk will be affected due to drug residues, and a large dose is required to reach the minimum inhibitory concentration (5 μg / g) of local endometrial tissue

Method used

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  • Traditional Chinese medicine composition for preventing and treating bovine uterine involution and its preparation method
  • Traditional Chinese medicine composition for preventing and treating bovine uterine involution and its preparation method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0040] The traditional Chinese medicine composition for preventing and treating bovine uterine involution is composed of the following components: 20g motherwort, 20g angelica, 20g astragalus, 20g white fresh bark, 15g corydalis, 20g mugwort, 20g salvia, 15g chuanxiong, 15g paojiang, 15g vinegar cyperus , 15g squid octopus, 15g Chuanduan, 15g forsythia, 15g borax, 15g mint, 15g Panax notoginseng, 15g white and, 15g licorice.

[0041] The preparation method of the traditional Chinese medicine composition perfusion agent for preventing and treating incomplete uterine involution of cattle comprises the following steps:

[0042] ①Pharmaceutical preparation: Weigh 10g motherwort, 20g angelica, 30g astragalus, 10g white fresh skin, 15g corydalis, 30g mugwort, 10g salvia, 15g chuanxiong, 20g paojiang, 10g vinegar Cyperus, 15g sea octopus, 20g chuanduan , 10g forsythia, 15g borax, 20g mint, 10g notoginseng, 15g white and, 20g licorice.

[0043] ② Boil medicine: add 2800ml of normal t...

Embodiment 2

[0051] The difference from Example 1 is that the traditional Chinese medicine composition for preventing and treating bovine uterine involution is composed of the following components: 20g motherwort, 30g angelica, 10g astragalus, 20g white fresh bark, 20g corydalis, 10g mugwort leaves, 20g salvia miltiorrhiza, 20g chuanxiong, 10g Paojiang, 15g Vinegar Cyperus, 20g Cuttlefish, 10g Chuanduan, 15g Forsythia, 20g Borax, 10g Mint, 15g Panax notoginseng, 20g Baiji, 10g Licorice.

[0052] The preparation method of the traditional Chinese medicine composition perfusion agent for preventing and treating incomplete uterine involution of cattle comprises the following steps:

[0053] ① Preparation of pharmaceuticals: 20g motherwort, 30g angelica, 10g astragalus, 20g white fresh skin, 20g corydalis, 10g mugwort, 20g salvia, 20g chuanxiong, 10g paojiang, 15g vinegar Cyperus, 20g sea octopus, 10g chuanduan, 15g Lianhua Qiao, 20g borax, 10g mint, 15g Sanqi, 20g white and 10g licorice.

[0...

Embodiment 3

[0059] The difference from Example 1 is that the traditional Chinese medicine composition for preventing and treating bovine uterine involution is composed of the following components: 30g motherwort, 10g angelica, 20g astragalus, 30g white fresh bark, 10g corydalis, 20g mugwort leaves, 30g salvia miltiorrhiza, 10g chuanxiong, 15g Paojiang, 20g Vinegar Cyperus, 10g Cuttlefish, 15g Chuanduan, 20g Forsythia, 10g Borax, 15g Mint, 20g Panax notoginseng, 10g Baiji, 15g Licorice.

[0060] The preparation method of the traditional Chinese medicine composition perfusion agent for preventing and treating incomplete uterine involution of cattle comprises the following steps:

[0061] ①Pharmaceutical preparation: Weigh 10g motherwort, 20g angelica, 30g astragalus, 10g white fresh skin, 15g corydalis, 30g mugwort, 10g salvia, 15g chuanxiong, 20g paojiang, 10g vinegar Cyperus, 15g sea octopus, 20g chuanduan , 10g forsythia, 15g borax, 20g mint, 10g notoginseng, 15g white and, 20g licorice....

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Abstract

A traditional Chinese medicine composition for preventing and treating bovine uterus subinvolution is composed of the following components in parts by weight: 10 to 30 parts of motherwort, 10 to 30 parts of Chinese angelica, 10 to 30 parts of radix astragali, 10 to 30 parts of dictamnus dasycarpus turcz, 10 to 20 parts of corydalis tuber, 10 to 30 parts of artemisia argyi, 10 to 30 parts of red sage root, 10 to 20 parts of ligusticum wallichii, 10 to 20 parts of roasted ginger, 10 to 20 parts of vinegar-processed rhizoma cyperi, 10 to 20 parts of cuttlebone, 10 to 20 parts of dipsacus root, 10 to 20 parts of fructus forsythiae, 10 to 20 parts of borax, 10 to 20 parts of mint, 10 to 20 parts of pseudo-ginseng, 10 to 20 parts of rhizoma bletillae, and 10 to 20 parts of licorice. The functions of core traditional Chinese herbals of motherwort, Chinese angelica, radix astragali, dictamnus dasycarpus turcz, corydalis tuber, artemisia argyi, and red sage root are integrated, at the same time auxiliary traditional Chinese herbals of ligusticum wallichii, roasted ginger, vinegar-processed rhizoma cyperi, cuttlebone, dipsacus root, fructus forsythiae, borax, mint, pseudo-ginseng, and rhizoma bletillae are added, and a proper preparation method is adopted to prepare the traditional Chinese medicine composition. The traditional Chinese medicine composition has functions of enhancing the uterus smooth muscle contraction, inhibiting bacterium, preventing inflammation, strengthening immunity, stopping bleeding, relieving pains, removing slough and promoting tissue regeneration, is capable of effectively preventing and treating bovine uterus subinvolution, reduces the uterus infection chance, and improves the bovine fertility.

Description

technical field [0001] The invention belongs to a veterinary drug composition, in particular to a traditional Chinese medicine composition and a preparation method thereof, in particular to a composition for preventing and treating incomplete involution of the bovine uterus and a preparation method thereof. Background technique [0002] The bovine uterus involution refers to the recovery of the bovine uterus to its prenatal volume and function within a certain period of time after delivery. Under normal circumstances, the bovine uterus returns to its non-pregnant volume about 30 days after delivery, and the bovine uterus completes involution after 5 to 6 weeks. However, postpartum cattle often have hormone disorders, retained placenta, weak uterine contraction, dystocia, too large fetus, excessive fetal water, twin pregnancy, uterine prolapse, postpartum hypocalcemia, and bacterial reproduction in the uterine cavity, which lead to The bovine uterus fails to return to the st...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9068A61K9/00A61P15/00
CPCA61K9/0031A61K33/22A61K35/618A61K36/185A61K36/232A61K36/236A61K36/258A61K36/282A61K36/481A61K36/484A61K36/533A61K36/534A61K36/537A61K36/634A61K36/66A61K36/75A61K36/8905A61K36/898A61K36/9068A61K2236/331A61K2236/39A61K2236/53A61K2300/00
Inventor 李华涛王新丛霞曹荣峰田文儒
Owner QINGDAO AGRI UNIV
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