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Sustained release micro-capsule and application thereof to anti-allergy face cream

A microcapsule, slow-release technology, applied in allergic diseases, cosmetic preparations, skin care preparations, etc., can solve the problems of no lasting anti-allergic effect, allergies, short-term anti-allergic effect, etc., to maintain anti-allergic effect Allergic effect, good sustained release effect, good embedding effect

Inactive Publication Date: 2015-02-25
CHONGQING PELLETS TECHN & TRADE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] However, the current anti-allergic products are all anti-allergic active ingredients are directly added to the product without certain protection, resulting in active ingredients being easily affected by adverse factors in the external environment during storage and losing their activity.
And more importantly, when the existing anti-allergic products are used, the anti-allergic active ingredients are released at one time to achieve a short-term anti-allergic effect, and do not have the function of lasting anti-allergic curative effect; and one-time release of large doses of Anti-allergic active ingredients, which may be too much for the skin and cause allergies instead

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] Polyethylene glycol 2000 is used as the main raw material of the capsule wall, and taro porous starch adsorbed with chamomile extract is the main raw material of the capsule core, wherein the chamomile extract can be obtained by supercritical carbon dioxide extraction. This embodiment is realized according to the following method:

[0020] (1) Weigh 500g of taro porous starch, in which the adsorption rate of taro porous starch to methylene blue is >93%. Under the condition of stirring, add accurately weighed 15g of chamomile extract, and under the condition of stirring, absorb for 1 hour to make the porous The starch is fully and evenly adsorbed to the chamomile extract.

[0021] (2) Weigh 1000g of polyethylene glycol 2000, heat it to 50°C to melt it completely, and add the taro prepared in step (1) to the melted polyethylene glycol with chamomile extract under stirring Porous starch, use a high-speed disperser to disperse the porous starch evenly in polyethylene glycol...

Embodiment 2

[0024] Polyethylene glycol 600 is used as the main raw material for the capsule wall, and the potato porous starch adsorbed with purslane extract is the main raw material for the capsule core. The purslane extract can be obtained by microwave-assisted extraction. This example follows the following method accomplish:

[0025] (1) Weigh 1000g of potato porous starch, add accurately weighed 100g of purslane extract under stirring conditions, and absorb for 0.5 h under stirring conditions, so that the porous starch is fully and evenly adsorbed to the purslane extract thing.

[0026] (2) Weigh 1667g of polyethylene glycol 600, heat it to 55°C to melt it completely, add the adsorbed purslane extract prepared in step (1) to the melted polyethylene glycol under stirring conditions Potato porous starch as a product, use a high-speed disperser to disperse the porous starch evenly in polyethylene glycol, then cool and solidify the mixed solution at room temperature, and then pulverize i...

Embodiment 3

[0029] Polyethylene glycol 12000 is used as the main raw material of the capsule wall, and cassava porous starch adsorbed with lavender extract is the main raw material of the capsule core, wherein the lavender extract can be obtained by ultrasonic-assisted extraction. This embodiment is realized according to the following method:

[0030] (1) Weigh 800g of cassava porous starch, add accurately weighed 120g of purslane extract under stirring conditions, and absorb for 1 hour under stirring conditions, so that the porous starch is fully and evenly adsorbed to the lavender extract.

[0031] (2) Weigh 1144g of polyethylene glycol 600, heat it to 55°C to melt it completely, add the cassava with lavender extract prepared in step (1) to the melted polyethylene glycol under stirring Porous starch, use a high-speed disperser to disperse the porous starch evenly in polyethylene glycol, then cool and solidify the mixed solution at room temperature, and then pulverize it until the average...

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PUM

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Abstract

The invention discloses a sustained release micro-capsule and application thereof to anti-allergy face cream. The sustained release micro-capsule is a spherical micro-capsule which is of a core-shell structure, a capsule wall contains polyethylene glycol, a capsule core contains porous starch, and anti-allergy active ingredients are adsorbed by the porous starch. The sustained release micro-capsule and the application have the advantages that the embedding rate of the sustained release micro-capsule can reach 94%, and a sustained release effect can be realized within 4h; the sustained release micro-capsule is added into the anti-allergy face cream, so that sustained release anti-allergy effects can be realized by the anti-allergy face cream, and allergic skin soothing effects can be effectively prolonged.

Description

technical field [0001] The invention belongs to the field of microcapsules, in particular to a slow-release microcapsule and its application in anti-allergic face cream. [0002] Background technique [0003] Improper use of cosmetics can cause allergic phenomena such as skin allergies, itching, scaling, redness, or redness. According to statistics from the Ministry of Health, skin allergies are caused by preservatives, flavors and fragrances, or surfactants in cosmetic ingredients. The incidence rate increases year by year, and the skin sensitivity problem is paid more and more attention by people. [0004] However, the current anti-allergic products are all anti-allergic active ingredients are directly added to the product without certain protection, resulting in active ingredients being easily affected by adverse factors in the external environment during storage and losing their activity. And more importantly, when the existing anti-allergic products are used, the anti...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/86A61K8/73A61K8/11A61K8/97A61Q19/08A61Q19/00A61P37/08A61P25/20
Inventor 袁彦洁
Owner CHONGQING PELLETS TECHN & TRADE
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