Pharmaceutical composition for treating osteoporosis

An osteoporosis and composition technology, applied in the directions of drug combinations, antipyretics, bone diseases, etc., can solve the problems of high price, obvious side effects, induced breast cancer, etc., and achieve the treatment of osteoporosis, no toxic side effects, and medication small dose effect

Inactive Publication Date: 2015-03-25
CHENGDU GUORUI PHARMA TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Most of these drugs are expensive and have obvious side effects
And there are related reports that long-term use of estrogen may induce breast cancer
Due to the difference in calcium absorption capacity of patients, the curative effect of calcitonin and calcium preparations is not satisfactory, and other therapies can only be used as adjuvant therapy
[0004] Therefore, the incidence rate of clinical osteoporosis is very high, but there is a lack of safe and effective drugs, and it is necessary to actively develop drugs for the treatment of osteoporosis.

Method used

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  • Pharmaceutical composition for treating osteoporosis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] The pharmaceutical composition for the treatment of osteoporosis described in the present embodiment is made of the raw materials of following weight:

[0036] Danshen 15g, Clematis 6g, Mianzi 6g, Panax notoginseng 6g, Tuyuan 9g and egg shell 3g.

[0037] Above-mentioned raw material is prepared into powder, and preparation method is as follows:

[0038] (1) Take Salvia miltiorrhiza, add 8 times the volume of 80% ethanol to reflux for extraction for 2 hours, collect the extract, concentrate, and dry to obtain the salvia miltiorrhiza extract.

[0039] (2) Take Clematis, add 8 times the volume of 80% ethanol to extract 3 times at 40° C., each time for 1.5 hours. The combined extracts were collected, concentrated, and dried to obtain Clematis clematis extract.

[0040] (3) Take the Herba Sinensis, add 8 times the volume of ethanol or water, reflux and extract three times, the extraction time is 2.0h, 1.5h, and 1.5h respectively, collect and combine the extracts and conce...

Embodiment 2

[0047] The pharmaceutical composition for the treatment of osteoporosis described in the present embodiment is made of the raw materials of following weight:

[0048] Danshen 28g, Clematis 3g, Mianzi 8g, Panax notoginseng 2g, Tuyuan 5g and egg shell 6g.

[0049] The above-mentioned raw materials are prepared into tablets, and the preparation method is as follows:

[0050] (1) Take Salvia miltiorrhiza, add 9 times the volume of 70% ethanol to reflux for extraction for 1 hour, collect the extract, concentrate, and dry to obtain the salvia miltiorrhiza extract.

[0051] (2) Take Clematis, add 9 times the volume of 70% ethanol to extract 3 times at 60° C., each time for 1.5 hours. The combined extracts were collected, concentrated, and dried to obtain the Clematis clematis extract.

[0052] (3) Take the Herba Sinensis, add 9 times the volume of ethanol or water, reflux and extract three times, the extraction time is 2.0h, 1.5h, and 1.5h respectively, collect and combine the extr...

Embodiment 3

[0059] The pharmaceutical composition for the treatment of osteoporosis described in the present embodiment is made of the raw materials of following weight:

[0060] Danshen 10g, Clematis 5g, Mianzi 3g, Panax notoginseng 9g, Tuyuan 5g and egg shell 1g.

[0061] The above-mentioned raw materials are prepared into granules, and the preparation method is as follows:

[0062] (1) Take Salvia miltiorrhiza, add 8 times the volume of 60% ethanol to reflux for extraction for 1 hour, collect the extract, concentrate, and dry to obtain the salvia miltiorrhiza extract.

[0063] (2) Take Clematis, add 8 times the volume of 70% ethanol to extract 3 times at 60° C., each time for 1.5 hours. The combined extracts were collected, concentrated, and dried to obtain Clematis clematis extract.

[0064] (3) Take the Herba Sinensis, add 9 times the volume of ethanol or water, reflux and extract three times, the extraction time is 2.0h, 1.5h, and 1.5h respectively, collect and combine the extract...

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Abstract

The invention discloses a pharmaceutical composition for treating osteoporosis. The pharmaceutical composition is prepared from salvia miltiorrhiza, radix clematidis, dioscorea septemloba, panax pseudo-ginseng, dried ground beetle bodies and egg shells. The pharmaceutical composition has the effects of tonifying the liver and kidneys and strengthening bone and alleviating pain, and can be used for effectively treating osteoporosis with manifestations of lumbar spinal pain, soreness, weakness, asthenia, dizziness, arthralgia, numbness of the limbs and the like. The pharmaceutical composition disclosed by the invention is definite in treatment effect, low in drug dosage and free from toxic or side effects on human bodies.

Description

technical field [0001] The invention relates to a pharmaceutical composition for treating osteoporosis, in particular to a pharmaceutical composition made from salvia miltiorrhiza, Clematis clematis, Mianzi, Panax notoginseng, Tuyuan and egg shells. Background technique [0002] Osteoporosis is a group of bone diseases caused by various reasons. There is normal calcification of bone tissue, and the ratio of calcium salt to matrix is ​​normal. It is a metabolic bone lesion characterized by a decrease in the amount of bone tissue per unit volume. In most cases of osteoporosis, the loss of bone tissue is mainly due to increased bone resorption. The onset is mostly slow, and individual is quicker. It is characterized by bone pain and easy fracture, and the biochemical examination is basically normal. [0003] At present, the treatment of this disease mainly relies on drug therapy, which generally includes estrogen replacement therapy, calcitonin and calcium preparations. Most ...

Claims

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Application Information

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IPC IPC(8): A61K36/8945A61P19/10A61P29/00A61K35/57A61K35/64
CPCA61K36/537A61K9/145A61K9/1652A61K9/2059A61K35/57A61K35/63A61K36/258A61K36/716A61K36/8945A61K2300/00
Inventor 李文军张玲成建国
Owner CHENGDU GUORUI PHARMA TECH
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