Freeze-dried excipient and matched solvent packaging double-cavity bag

Abstract

The invention relates to a freeze-dried excipient and a matched solvent packaging double-cavity bag, in particular to a double-cavity bag which enables a freeze-dried excipient applied to foods or health foods or oral drugs or topical drugs or cosmetics and a solvent to be independently stored and used in the same package and prepared to be readily available. The packaging double-cavity bag for the freeze-dried excipient has the advantages of protecting the stability of active ingredients, achieving single-dose packaging, being convenient to carry and use, avoiding contamination, lowering the cost and the like.

Description

technical field [0001] The invention relates to a freeze-dried excipient preparation and a double-chamber bag for matching solvent packaging, in particular to a freeze-dried excipient preparation applied to food, health food, oral medicine, external medicine and cosmetics, which is combined with a solvent in the same It is a double-chamber bag that is stored separately in the package and ready to use when used. Background technique [0002] Freeze-dried excipient preparation is a preparation form prepared by freeze-dry excipient technology. It is formed by pouring the raw and auxiliary materials of the preparation into the molding mold and then undergoing a freeze-drying process. Because this type of preparation adopts the freeze-drying process, it can protect heat-sensitive ingredients, effective nutrients, and easily oxidized substances from being destroyed, and can be stored for a long time without deterioration. It is widely used in orally disintegrating tablets, immedi...

AI Technical Summary

Problems solved by technology

[0003] At present, most of the packaging devices selected by the preparations prepared by freeze-drying technology are double-aluminum packaging to ensure their oxygen and moisture barrier properties, but they need to be mixed with water or solvents before use, which is extremely inconvenient to operate. easy to cause secondary pollution

[0004] Traditional pre-filled dual-chamber syringes are mainly used for injection purposes, and the design is complicated and the production cost is high; at the same time, because the traditional freeze-drying system is based on small molecular sugars, sugar alcohols and amino acids. The dry powder form is very sensitive to physical and mechanical forces. If in-situ freeze-drying is not used, it is very easy to break, resulting in inaccurate dosage. At the same time, the broken or falling freeze-dried pulverized pieces will also affect the assembly and processing of pre-filled dual-chamber syringes. Big problem with using

There is also a type of double-chamber bag for co-extrusion infusion commonly used in the field of pharmaceutical packaging, which adopts a double-chamber design. , "false welding" and other technologies, these technologies are either complex in design and high in production costs, or the welds are easily cracked and cannot withstand a certain pressure, and it is easy to open the two chambers during transportation and storage

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