Method for preparing absorbable suture
A technology of sutures and collagen fibers, applied in the field of sutures, can solve the problems of suture quality influence, material hydrolysis deterioration, mechanical strength decline, etc., to achieve the effects of accelerating wound healing, avoiding infection, and stabilizing the absorption period
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[0020] Example 1
[0021] The present invention is used to prepare an absorbable suture thread, and its preparation method includes the following steps:
[0022] (1) Isolate protein chorionic membrane: select fresh goat casings, wash the inner wall of the casing, and scrape the chorionic membrane, mucosa, serous membrane, etc. in the casing to make it fall off;
[0023] (2) Collagen fiber purification: clean the sheep casings with water, soak them in 0.9% sodium chloride solution for 30 minutes, take them out and soak them in 30% sodium chloride solution for 10 minutes, and then separate and remove them. The fat in the collagen fiber obtains relatively pure collagen fiber;
[0024] (3) Degreasing and degreasing: Add the purified collagen fiber to a 0.5% sodium hydroxide solution at a temperature of 40 degrees Celsius and soak for 15 minutes. The solution also contains 1% lauryl sulfuric acid by weight. Sodium, which separates all the grease between the collagen fibers, clean it with ...
Example Embodiment
[0031] Example 2
[0032] The present invention is used to prepare an absorbable suture thread, and its preparation method includes the following steps:
[0033] (1) Isolate protein chorionic membrane: select fresh goat casings, wash the inner wall of the casing, and scrape the chorionic membrane, mucosa, serous membrane, etc. in the casing to make it fall off;
[0034] (2) Collagen fiber purification: clean the sheep casings with water, soak them in 0.9% sodium chloride solution for 30 minutes, take them out and soak them in 30% sodium chloride solution for 10 minutes, and then separate and remove them. The fat in the collagen fiber obtains relatively pure collagen fiber;
[0035] (3) Degreasing and degreasing: Add the purified collagen fibers to a 2% sodium hydroxide solution at a temperature of 60 degrees Celsius and soak for 10 minutes. The solution is also added with 0.5% dodecylbenzene by weight. Sodium sulfonate, so that all the grease between the collagen fibers is separated ...
Example Embodiment
[0042] Example 3
[0043] The present invention is used to prepare an absorbable suture thread, and its preparation method includes the following steps:
[0044] (1) Isolate protein chorionic membrane: select fresh goat casings, wash the inner wall of the casing, and scrape the chorionic membrane, mucosa, serous membrane, etc. in the casing to make it fall off;
[0045] (2) Collagen fiber purification: clean the sheep casings with water, soak them in 0.9% sodium chloride solution for 30 minutes, take them out and soak them in 30% sodium chloride solution for 10 minutes, and then separate and remove them. The fat in the collagen fiber obtains relatively pure collagen fiber;
[0046] (3) Degreasing and degreasing: Add the purified collagen fibers to a 1.5% sodium hydroxide solution at a temperature of 55 degrees Celsius and soak for 12 minutes. The solution is also added with 0.8% sodium stearate by weight. Separate all the grease between the collagen fibers, clean it with water and se...
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