Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Crystallizing device for preparing high-purity rebaudioside A by employing continuous purification, and control method of crystallizing device

A crystallization device and high-purity technology, applied in chemical instruments and methods, solution crystallization, preparation of sugar derivatives, etc., can solve the problem of high energy consumption, production cost and waste discharge, inability to realize batch continuous production, and discrete unit operation process. and other problems, to achieve the effect of automatic continuous production, stable and reliable production system, and simple equipment

Active Publication Date: 2015-04-29
ZHEJIANG UNIV
View PDF8 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] However, the commonality and bottleneck problems of the above technologies are that the single crystallization cycle is long, the yield is low, and the quality stability is poor.
In particular, they are all about technological development, without the invention content of equipment and devices
There is no integration between each unit, the unit operation process is discrete, the waiting time for equipment is long, batch continuous production cannot be realized, and energy consumption, production cost and waste discharge are relatively high
There are no invention patents on how to deal with the crystallization mother liquor, how to improve the utilization rate of raw materials, etc.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Crystallizing device for preparing high-purity rebaudioside A by employing continuous purification, and control method of crystallizing device
  • Crystallizing device for preparing high-purity rebaudioside A by employing continuous purification, and control method of crystallizing device
  • Crystallizing device for preparing high-purity rebaudioside A by employing continuous purification, and control method of crystallizing device

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0041] Described stevioside raw material (RA content is about 50%, its HPLC detection result is as attached image 3 Shown) mixed with methanol solution at a solid-to-liquid ratio of 1:8, sent to the stirring tank 2, stirred and dissolved, and hot water at 50°C was passed through the jacket from bottom to top, after stirring for 5 minutes, press the valve in Table 1 above The control flow is sent into static tanks AB1-AB6 in turn, and crystallized in static tanks AB1-AB6 for 0.5h, solid-liquid separation, and the HPLC detection result of the primary crystallization crystal is as follows: Figure 4 Shown; Mix the primary crystallized product with methanol aqueous solution at a solid-to-liquid ratio of 1:8, and send them into the stirring tank CD1-CD6 in chronological order, and pass hot water at 60°C from bottom to top in the jacket, and stir for 10 minutes. , Feed liquid is sent in corresponding static tank, static crystallization 9h, solid-liquid separation, get high-purity R...

Embodiment 2

[0045] The stevioside raw material (RA content is about 50%) is mixed with methanol solution at a solid-to-liquid ratio of 1:5, sent into the stirring tank 2, stirred and dissolved, and hot water at 35°C is passed through the jacket from bottom to top, and stirred for 15 minutes Afterwards, according to the valve control flow process in above Table 1, send into static tank AB1-AB6 successively, in static tank AB1-AB6, static crystallization 1h, solid-liquid separation; The liquid ratio is 1:10 and mixed, and sent to the stirring tank CD1-CD6 in sequence in time, and the hot water of 40°C is passed through the jacket from bottom to top, and after stirring for 15 minutes, the material liquid is sent to the corresponding static tank. Static crystallization for 10 hours, solid-liquid separation, to obtain high-purity RA crystals; primary crystallization and secondary crystallization mother liquor are evaporated and dried, methanol is recovered, sent to methanol storage tank for rec...

Embodiment 3

[0049]The stevioside raw material (RA content is about 50%) is mixed with methanol solution at a solid-to-liquid ratio of 1:10, sent into the stirring tank 2, stirred and dissolved, and 60°C hot water is passed through the jacket from bottom to top, and stirred for 20 minutes Finally, according to the valve control flow process in above table 1, send into static tank AB1-AB6 successively, in static tank AB1-AB6, static crystallization 40min, solid-liquid separation; Mix liquid at a ratio of 1:5, and send them into the stirring tanks CD1-CD6 in chronological order, pass hot water at 70°C from bottom to top in the jacket, and after stirring for 30 minutes, send the material liquid into the corresponding static tank. Static crystallization for 5 hours, solid-liquid separation, and high-purity RA crystals were obtained; primary crystallization and secondary crystallization mother liquor were evaporated and dried, methanol was recovered, and sent to a methanol storage tank for recyc...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to a purifying preparation technology of RA, in particular to a crystallizing device for preparing high-purity rebaudioside A by employing continuous purification, and a control method of the crystallizing device. The crystallizing device comprises a primary crystallization area, a secondary crystallization area and a post-treatment area, wherein the primary crystallization area is formed by sequential connection of a first storage tank, a second stirring tank, a primary standing tank, a centrifugal filtering device, an evaporation tank and a drying device through a pipeline; the secondary crystallization area comprises a secondary stirring tank, a secondary standing tank and a centrifugal filtering device; the secondary stirring tank is connected with the secondary standing tank through a pipeline; the secondary standing tank is connected with the centrifugal filtering device through a pipeline; and the post-treatment area comprises a second storage tank, a third storage tank, a first stirring tank and a centrifugal filtering device. The crystallizing system has the advantage of controllable crystallization process; through control of the crystallization time of each area, the crystallization cycle and the yield reach the optimal balanced point; and the crystallization period is shortened, so that the optimal separation effect is reached.

Description

technical field [0001] The invention relates to the purification and preparation technology of rebaudioside A (RA), in particular to a continuous purification and preparation of high-purity rebaudioside A crystallization device and a control method thereof. Background technique [0002] Stevioside (glycoside) is a new type of natural sweetener extracted from Stevia rebaudiana. It has the characteristics of high sweetness, low calorie, good taste, safety and non-toxicity. It is a natural sweetener with great development value after sucrose and saccharin , known as "the third sugar source in the world". In stevioside, STV (steviol glycoside) and RA (rebaudioside A) are the two main sweet components, and the sweetness is relatively high, among which the sweetness of STV is 150-300 times that of sucrose, and the sweetness of RA is The density is 350-450 times that of sucrose. Stevioside is expected to replace sucrose in food, beverage and other industries, but the bitterness o...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): B01D9/02C07H15/256C07H1/06
Inventor 杨健沈建
Owner ZHEJIANG UNIV
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com