Medicinal toothpaste composition and preparation method and application thereof

Abstract

The invention discloses a medicinal toothpaste composition which comprises the following raw materials in percentage by weight: 0.01%-0.05% of sodium guaiazulene sulfonate, 0.1%-0.5% of paeonol, 0.1-0.5w / w% of allantoin, 0.1-0.5w / w% of tranexamic acid, and toothpaste matrix on the basis of the total weight. In addition, the invention further discloses a preparation method of the medicinal toothpaste composition and applications in resisting bacteria, diminishing inflammation, easing pain, shortening the treatment course of dental ulcer, and promoting oral wound healing.

Description

technical field [0001] The invention relates to the field of daily chemical technology, in particular to a pharmaceutical toothpaste composition capable of significantly inhibiting plaque bacteria, reducing gingival inflammation, reducing the course of oral ulcers, and relieving pain, as well as its preparation method and application. Background technique [0002] Oral health is one of the hallmarks of modern human civilization. Having a healthy mouth can enjoy delicious food and express one's wishes clearly. A healthy mouth can also make people full of confidence and laugh. Oral health is a mirror of overall health. Many systemic diseases are manifested in the oral cavity. For example, diabetic patients often have poor periodontal conditions. On the other hand, oral diseases can affect the health of the whole body. For example, in severe periodontal disease, pathogenic bacteria and toxins around the teeth can enter the blood, aggravating the systemic symptoms of diabetic pa...

AI Technical Summary

Problems solved by technology

[0005] At present, there are some literature and patent reports on the application of sodium azulene sulfonate in toothpaste and the compatibility of Chinese herbal medicines, but in general, there are deficiencies such as complex components, cumbersome processes, and inaccurate curative effects.

[0006] For example, the formula disclosed in Chinese patent application CN200910304069.2 adopts the structure of Chinese herbal medicine-enzyme preparation-azulene sulfonate-antisensitizer, and has many ingredients. The amount of Sanqi extract used in it is large and the purity is low, which will inevitably affect its effect. , after compounding with sodium azulene sulfonate, it is necessary to add enzyme preparation for compound synergistic effect, which undoubtedly increases the production cost, and the enzyme preparation has poor stability and is not easy to store and use, so the storage cost is bound to increase accordingly

Moreover, the above-mentioned patents do not measure the actual antibacterial and anti-inflammatory effects of the toothpaste.

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