Method for establishing tumor multi-drug resistant cell mode and human breast cancer multi-drug resistant cell strain established by virtue of method
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- HENAN UNIVERSITY
- Publication Date
- 2015-07-01
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Abstract
Description
technical field
[0001] The invention belongs to the field of tumor biology, and in particular relates to a method for producing a mold constructing an in vitro tumor multidrug-resistant cell model by a single-machine reaction oxygen group, and also relates to a human breast cancer multidrug-resistant cell line established by the method. Background technique
[0002] The construction of tumor cell models in vitro is an important experimental basis for the study of tumor occurrence, development and intervention. The choice of modeling conditions and modeling methods is the decisive factor for model construction. It is a key platform for revealing the molecular mechanism of similar tumor formation and studying tumor drug intervention. .
[0003] Tumor multidrug resistance (MDR) refers to the phenomenon that tumor cells develop drug resistance after exposure to antineoplastic drugs, and also produce cross-resistance to a variety of antineoplastic drugs with different structures...