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Composition with itching removing function and preparation method thereof

A composition and functional technology, applied in the direction of medical preparations containing active ingredients, drug combinations, skin care preparations, etc., can solve the problems of large side effects, complex ingredients, greasy and uncomfortable skin, etc., and achieve low production cost and good quality. Compatibility, the effect of product quality stability

Active Publication Date: 2015-07-22
广西厚德药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

It overcomes the shortcomings of the current antipruritic topical drugs on the market, such as complex ingredients, large side effects, greasy skin and discomfort when used

Method used

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  • Composition with itching removing function and preparation method thereof
  • Composition with itching removing function and preparation method thereof
  • Composition with itching removing function and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0079] Embodiment 1: Comparative test of human trial effect of different formula products

[0080] The advantages of the present invention are further illustrated by comparing the antipruritic effect, effective antipruritic time, moisturizing effect, and allergic reaction of different formula products after human trials.

[0081] The products prepared with the formula in Table 1 were given to different people for trial respectively, and the antipruritic effect, effective antipruritic time, moisturizing effect, allergic reaction, etc. were investigated after use.

[0082] Table 1 Comparative formula

[0083]

[0084] Compare the preparation methods of formulas 1 to 5 (if there is no such ingredient in the formula, do not add it):

[0085] a. Heat cetearyl alcohol, liquid paraffin, ceteareth-6, ceteareth-25, and tocopheryl acetate in a jacketed pot to 70-75°C and stir to dissolve , and kept warm for 10 minutes to obtain solution A;

[0086] b. After acrylic acid (ester) / C1...

Embodiment 2~10

[0125] The composition of embodiment 2~10 pharmaceutical compositions: unit (%)

[0126]

[0127] Preparation

[0128] The pharmaceutical compositions of "Example 2" to "Example 10" mentioned above can be prepared by any conventional method well known in the art. They can be suitably prepared as follows:

[0129] a. Heat cetearyl alcohol, liquid paraffin, ceteareth-6, ceteareth-25, and tocopheryl acetate in a jacketed pot to 70-75°C and stir to dissolve , and kept warm for 10 minutes to obtain solution A;

[0130] b. After acrylic acid (ester) / C10-30 alkanol acrylate crosslinked polymer is fully wetted with purified water, add allantoin and ammonium glycyrrhizinate and stir, heat the jacketed pot to 70-75°C, and stir to make it Dissolve and keep warm for 10 minutes to obtain solution B;

[0131] c. Add solutions A and B into the emulsification pot to emulsify evenly, turn on the homogenizer to homogenize for 5 minutes, add triethanolamine, keep stirring for 10 minutes, ...

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PUM

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Abstract

The invention discloses a composition with itching removing function, the composition is prepared by addition of camphor, borneol, ammonium glycyrrhetate, allantoin and other components with itching removing function on the basis of antimicrobial itching-removing traditional Chinese medicines, and the composition has good itching removing effect, is quick in itching removing effect on a variety of skin itch, short in action time, non-toxic and free of side effects.

Description

technical field [0001] The invention relates to a composition and a preparation method thereof, in particular to a composition with an antipruritic function and a preparation method thereof. Background technique [0002] Almost everyone has the experience of skin itching. There are many reasons for skin itching. The reasons are believed to be itching caused by skin inflammation, dryness, infection or internal diseases. In addition, climate effects such as hot, humid, cold, dry, mosquito bites Skin itching caused by unknown reasons such as allergies and allergies often plagues people. Although itchy skin is a minor ailment, it can be upsetting, restless, and even painful. [0003] Western medicine believes that skin itching is related to the participation of several mediators such as histamine, 5-hydroxytryptamine, endogenous opioid peptide system, cytokines, etc. At present, antihistamines are generally administered orally or hormone drugs are used externally, but drowsines...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/185A61K8/97A61P17/04A61Q19/00A61K31/4166A61K31/045A61K31/125
Inventor 阮碧芳李品梁峰罗桂容黄园梁月钊
Owner 广西厚德药业有限公司
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