Composition with itching removing function and preparation method thereof
A composition and functional technology, applied in the direction of medical preparations containing active ingredients, drug combinations, skin care preparations, etc., can solve the problems of large side effects, complex ingredients, greasy and uncomfortable skin, etc., and achieve low production cost and good quality. Compatibility, the effect of product quality stability
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Embodiment 1
[0079] Embodiment 1: Comparative test of human trial effect of different formula products
[0080] The advantages of the present invention are further illustrated by comparing the antipruritic effect, effective antipruritic time, moisturizing effect, and allergic reaction of different formula products after human trials.
[0081] The products prepared with the formula in Table 1 were given to different people for trial respectively, and the antipruritic effect, effective antipruritic time, moisturizing effect, allergic reaction, etc. were investigated after use.
[0082] Table 1 Comparative formula
[0083]
[0084] Compare the preparation methods of formulas 1 to 5 (if there is no such ingredient in the formula, do not add it):
[0085] a. Heat cetearyl alcohol, liquid paraffin, ceteareth-6, ceteareth-25, and tocopheryl acetate in a jacketed pot to 70-75°C and stir to dissolve , and kept warm for 10 minutes to obtain solution A;
[0086] b. After acrylic acid (ester) / C1...
Embodiment 2~10
[0125] The composition of embodiment 2~10 pharmaceutical compositions: unit (%)
[0126]
[0127] Preparation
[0128] The pharmaceutical compositions of "Example 2" to "Example 10" mentioned above can be prepared by any conventional method well known in the art. They can be suitably prepared as follows:
[0129] a. Heat cetearyl alcohol, liquid paraffin, ceteareth-6, ceteareth-25, and tocopheryl acetate in a jacketed pot to 70-75°C and stir to dissolve , and kept warm for 10 minutes to obtain solution A;
[0130] b. After acrylic acid (ester) / C10-30 alkanol acrylate crosslinked polymer is fully wetted with purified water, add allantoin and ammonium glycyrrhizinate and stir, heat the jacketed pot to 70-75°C, and stir to make it Dissolve and keep warm for 10 minutes to obtain solution B;
[0131] c. Add solutions A and B into the emulsification pot to emulsify evenly, turn on the homogenizer to homogenize for 5 minutes, add triethanolamine, keep stirring for 10 minutes, ...
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