Coptis chinensis donkey-hide gelatin composition for treating insomnia and preparation method of coptis chinensis donkey-hide gelatin composition
A composition and technology for insomnia, applied in the direction of drug combinations, medical preparations containing active ingredients, pharmaceutical formulas, etc., can solve problems such as unsatisfactory curative effects, achieve good effects in treating insomnia, satisfy clinical effects, and improve sleep The effect of obstacles
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Embodiment 1
[0035] Embodiment 1: the preparation of capsule
[0036] (1) Weigh each raw material according to the following weight: Coptis chinensis 800g, donkey-hide gelatin 900g, red peony root 600g, fried jujube seed 1000g, cinnamon 200g, Albizia juniper 600g, Baiwei 700g, ephedra 400g, cicada slough 600g, Shichangpu 1000g, rehmannia glutinosa 1500g;
[0037] (2) Extract the volatile oil from cinnamon and calamus calamus, wrap the volatile oil with β-cyclodextrin and crush it, set aside;
[0038] (3) extract the dregs after extracting the volatile oil, Albizia Julibrissin, cicada slough, rehmannia glutinosa, and ephedra with water twice, add 8 times the weight of water for the first time, decoct for 2 hours, add 6 times the weight of water for the second time, and decoct for 1 hour; Combine the decoction liquids, filter, concentrate the filtrate to a relative density of 1.30-1.35 (55°C), clear the paste, spray dry it, and set aside;
[0039] (4) Extract Coptidis Rhizoma, Radix Paeoni...
Embodiment 2
[0041] Embodiment 2: the preparation of capsule
[0042] Prescription composition:
[0043] Coptidis 200g Donkey-hide gelatin 225g Chishao 150g Baiwei 175g Ephedra 100g
[0044] 375g cooked ground, 50g cinnamon, 150g acacia skin, 150g cicada slough, 250g calamus
[0045] Fried Suanzaoren 250g
[0046] Preparation Process:
[0047] (1) Coptidis, Radix Paeoniae Rubra, Fried Jujube Seed, and Bai Wei are extracted twice with 6 times of 70% ethanol, 1.5 hours each time, filtered, and the filtrate is concentrated to a relative density of 1.08-1.10 (60°C) after recovering ethanol, and sprayed Dried to obtain fine powder for subsequent use;
[0048] (2) Add 12 times the amount of water to cinnamon and calamus, soak for 3 hours, extract the volatile oil for 3.5 hours, store the volatile oil and water extract separately for later use, and save the dregs for later use; add 10 times the amount of β-cyclodextrin to the volatile oil and then add β - Mix 20% ethanol with 3 times the a...
Embodiment 3
[0051] Example 3: Preparation of powder
[0052] Weigh each crude drug by the following weight: Coptidis 600g, donkey-hide gelatin 700g, red peony root 400g, fried jujube seed 400g, cinnamon 50g, Albizia acacia bark 400g, Baiwei 400g, ephedra 200g, cicada slough 400g, Shichangpu 800g, rehmannia glutinosa 1000g; After the crude drug is pulverized, it is passed through an 80-mesh sieve, and then packaged separately to obtain the product.
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