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A compound traditional Chinese medicine for treating neonatal jaundice

The technology of a traditional Chinese medicine and a compound prescription is applied to the traditional Chinese medicine compound prescription for the treatment of neonatal jaundice and the preparation field thereof, and can solve the problems of high mortality rate, bilirubin encephalopathy and the like, and achieve the effects of high safety, exact course of treatment and short course of treatment.

Inactive Publication Date: 2016-03-23
岳凌霄 +2
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] Neonatal jaundice (fetal yellow) is one of the common symptoms in the newborn period, especially for newborns within one week. However, when there are high-risk factors such as hypoxia, acidosis, and infection at the same time, it can cause bilirubin encephalopathy with high mortality, and most survivors have long-term neurological sequelae

Method used

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  • A compound traditional Chinese medicine for treating neonatal jaundice
  • A compound traditional Chinese medicine for treating neonatal jaundice

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0075] The preparation of embodiment 1 granule

[0076] Prescription (by weight):

[0077] Yin Chen 30, Gardenia 20, Dried Ginger 20, Albizia Julibrissin 16, Rhubarb 8, Milk Thistle 20, Lianmoyao 10, Bupleurum 16.

[0078] Preparation method: put dried ginger, bupleurum, rhubarb, milk thistle, capillary, gardenia, saffron and acacia bark in parts by weight of the present invention into a container, add 10 times parts by weight of water, and soak for 2 hours , decoct for 2 hours, and filter; add 6 times the amount of distilled water to the filter residue, decoct for 1 hour, and filter; combine the two filtrates, concentrate to a thick paste with a relative density of 1.20-1.25 at 65°C, add starch, sucrose, etc. Excipients, prepared into granules, sterilized, packed into bags, 2.5g per bag, containing 1.5g of crude drug.

Embodiment 2

[0079] The preparation of embodiment 2 oral liquid

[0080] Prescription (by weight):

[0081] Yin Chen 40, Gardenia 30, Dried Ginger 24, Albizia Julibrissin 24, Rhubarb 24, Milk Thistle 24, Lianmoyao 24, Bupleurum 12.

[0082] Preparation method: put dried ginger, bupleurum, rhubarb, milk thistle, capillary, gardenia, saffron and acacia bark in parts by weight of the present invention into a container, add 10 times parts by weight of water, and soak for 2 hours , decoct for 2 hours, filter; add 6 times the amount of distilled water to the filter residue, decoct for 1 hour, filter; combine the two filtrates, concentrate to a thick paste with a relative density of 1.20-1.25 at 65°C, add sucrose and dextrin and other auxiliary materials are prepared into oral liquid, sterilized, and filled, each bottle is 100ml, containing 30g of crude drug.

Embodiment 3

[0083] The preparation of embodiment 3 granules

[0084] Prescription (by weight):

[0085] Yin Chen 16, Gardenia 6, Dried Ginger 6, Albizia Julibrissin 8, Rhubarb 4, Milk Thistle 4, Lianmoyao 64, Bupleurum 64.

[0086] Preparation method: put dried ginger, bupleurum, rhubarb, milk thistle, capillary, gardenia, saffron and acacia bark in parts by weight of the present invention into a container, add 10 times parts by weight of water, and soak for 2 hours , decoct for 2 hours, and filter; add 6 times the amount of distilled water to the filter residue, decoct for 1 hour, and filter; combine the two filtrates, concentrate to a thick paste with a relative density of 1.20-1.25 at 65°C, add starch, sucrose, etc. Excipients, prepared into granules, sterilized, packed into bags, 2.5g per bag, containing 1.5g of crude drug.

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Abstract

The invention belongs to the field of medicines and relates to a compound traditional Chinese medicine for treating neonatal jaundice. The compound traditional Chinese medicine is prepared from the following traditional Chinese medicines: herba artemisiae scopariae, cape jasmine, rhizoma zingiberis, cortex albiziae, rheum officinale, silybum marianum, glechoma hedracea and radix bupleuri. Common herbs are optimized in the compound traditional Chinese medicine, and the compound traditional Chinese medicine has the advantages of small dosage, high effective rate, definite treatment course, short treatment course and the like in treating neonatal jaundice, and is especially suitable for treating neonatal interior damp-heat accumulation type jaundice.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a Chinese medicine compound for treating neonatal jaundice and a preparation method thereof. Background technique [0002] Neonatal jaundice (fetal yellow) is one of the common symptoms in the newborn period, especially for newborns within one week. However, when there are high-risk factors such as hypoxia, acidosis, and infection at the same time, bilirubin encephalopathy can be caused, and the mortality rate is high. Survivors often have long-term neurological sequelae. [0003] Fetus jaundice is a disease with yellowing of the skin and sclera of the whole body after birth due to damp heat or internal resistance of stagnant heat during the fetal period. Syndromes are divided into the following three categories: internal dampness and heat: yellow face and skin, bright color, orange-like shape, irritability and crying, yellow and red urine, cons...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9068A61P1/16
Inventor 蒋凤霞王健康
Owner 岳凌霄
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