Biochip

Abstract

A biochip comprising: a vessel; a liquid which is contained in the vessel; and an additive which is a carbinol-modified silicone resin, a carboxyl-modified silicone resin, an amino-modified silicone resin, a polyether-modified silicone resin, a silanol-modified silicone resin, or a fluoro-modified silicone resin, wherein a liquid droplet of a reaction mixture which (i) has a different specific gravity from that of the liquid; (ii) is immiscible with the liquid and (iii) contains a surfactant, can move in the longitudinal direction of the vessel when placed in the vessel.

Description

technical field [0001] The invention relates to a biological chip. Background technique [0002] In recent years, with the development of gene utilization technology, medical treatment using genes such as gene diagnosis and gene therapy has attracted much attention. In addition, many methods of using genes for variety identification and variety improvement have been developed in the field of agriculture and animal husbandry. Nucleic acid amplification techniques such as the PCR (Polymerase Chain Reaction: Polymerase Chain Reaction) method are widely used as techniques utilizing genes. Today, the PCR method has become an indispensable technique for information analysis of biological substances. [0003] In the PCR method, a method of performing a reaction using a container for performing a biochemical reaction called a tube or a chip (hereinafter referred to as a biochip) is generally used. However, in the conventional method, there are problems that the required amount of ...

AI Technical Summary

Problems solved by technology

In this state, if PCR is performed in the method of moving the reaction solution by gravity in the biochip (hereinafter, this method is referred to as "lifting type" in this specification) as described in Patent Document 1, then Sometimes the reaction solution does not move properly and the desired thermal cycle cannot be performed

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