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Micro-ecology and Chinese herbal medicine compound preparation for treating gastrointestinal diseases and preparation method thereof

A compound preparation and technology for gastrointestinal diseases, applied in the field of medicine, can solve the problems of high production cost, complicated preparation process, and short shelf life, and achieve the effects of eliminating gastric inflammation, improving gastric immunity, and enhancing defense capabilities

Inactive Publication Date: 2015-10-21
上海善力健生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the preparation process of the strain is complicated, the shelf life is short, the requirements are high, and the production cost is high

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] A compound preparation of microecology and Chinese herbal medicine for treating gastrointestinal diseases. The raw materials used include: live microecological probiotics and their fermentation complexes, lactoferrin, Hericium erinaceus extract, extract, and dandelion extract, wherein:

[0022] Micro-ecological probiotic live bacteria and its fermentation complex 30-40, lactoferrin 5-10, Hericium erinaceus extract 15-20, extract 10-15, dandelion extract 10-15.

[0023] The micro-ecological probiotic live bacteria and their fermentation complexes are obtained by the following method: Lactobacillus is inoculated in a fermenter, and the ventilation rate is 0.8-1.6m 3 / h, the fermentation temperature is 25-28°C, the fermentation time is 36-48 hours, the fermentation liquid is taken out of the tank and centrifuged at 6000-8000rpm at a high speed to obtain a precipitate, which is dried to obtain the final product.

[0024] The lactoferrin is obtained by the following method: ...

Embodiment 2

[0037] The compound preparation of microecology and Chinese herbal medicine for treating gastrointestinal diseases is prepared by the following method: by weight parts, microecological probiotic live bacteria and its fermentation complex 30, lactoferrin 5, Hericium erinaceus extract 20, extract 15, Dandelion extract 15, mixed at room temperature for 20 minutes, passed through a 60-80 mesh sieve, and repeated twice to obtain the final product. The related clinical trials of the obtained biological preparations for 2 months showed that the negative conversion rate of Helicobacter pylori reached 70%.

Embodiment 3

[0039] The microecological and Chinese herbal medicine compound preparation for treating gastrointestinal diseases is prepared by the following method: by weight, 40 live microecological probiotics and their fermentation complexes, 10 lactoferrin, 15 Hericium erinaceus extracts, 10 extracts, Dandelion extract 10, mixed at room temperature for 15 minutes, passed through a 60-80 mesh sieve, and repeated twice to obtain the final product. The related clinical trials of the obtained biological preparations for 2 months showed that the Helicobacter pylori negative conversion rate reached 72%.

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Abstract

The invention relates to a micro-ecology and Chinese herbal medicine compound preparation for treating gastrointestinal diseases and a preparation method thereof. 30-40 parts of micro-ecology probiotic viable bacteria and fermented compounds thereof, 5-10 parts of lactoferrin, 15-20 parts of hericium erinaceus extract, 10-15 parts of fructus mume extract and 10-15 parts of dandelion extract are mixed by weight at the normal temperature. Compared with the prior art, according to the micro-ecology and Chinese herbal medicine compound preparation for treating the gastrointestinal diseases and the preparation method thereof, the micro-ecology probiotic (lactobacilli and the like) viable bacteria and the fermented product compounds thereof aim at protecting gastrointestinal mucosae to restrain the activity of helicobacter pylori. Chinese herbal medicine ingredients enhance defense capability of gastrointestinal mucosa epithelial cells for H<+>, and meanwhile the repairing and nutritious functions for the mucosae are achieved.

Description

technical field [0001] The invention relates to a medicine, in particular to a composite preparation of microecology and Chinese herbal medicine for treating gastrointestinal diseases related to Helicobacter pylori and a preparation method thereof. Background technique [0002] With the progress of modern medical research, it has been shown that diseases such as gastritis and enteritis are highly correlated with gastric Helicobacter pylori in the human body. 67%-80% of gastric ulcers and 95% of duodenal ulcers are related to Helicobacter pylori infection. [0003] At present, the treatment methods for such diseases are mostly antibiotic-based combined drug regimens, but with the increase in the use of antibiotics, the side effects are also greater. [0004] The Chinese patent application number 201280012521.8 discloses a strain of Bifidobacterium bifidum used in gastrointestinal diseases. The "variant" of the strain of the invention is a naturally occurring variant, that is...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K38/40A61P1/04A61P1/00A61K36/288A61K36/736A61K36/06A61K35/747
Inventor 许宏华韩超
Owner 上海善力健生物科技有限公司
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