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Bactericide and application thereof

A technology of fungicides and surfactants, applied in the field of high-efficiency fungicides, can solve the problems of inability to kill bacteria, difficult to deal with, and low bactericidal effect.

Active Publication Date: 2015-11-04
NINGBO RUNZENG MEDICAL SCI & TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The advantages of low-efficiency disinfectant quaternary ammonium salts and biguanide fungicides are that they are less corrosive to objects, less polluting to the environment, less irritating to the human body, and less toxic, but their bactericidal effect is also very low, whether used alone or mixed It cannot kill many strains even if used, and it is difficult to cope with the large-scale epidemic viruses that have appeared frequently since the 21st century, such as SARS, bird flu, swine flu, etc.

Method used

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  • Bactericide and application thereof
  • Bactericide and application thereof
  • Bactericide and application thereof

Examples

Experimental program
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Effect test

Embodiment Construction

[0060] The experimental methods used in the following examples are conventional methods unless otherwise specified.

[0061] The materials and reagents used in the following examples can be obtained from commercial sources unless otherwise specified.

[0062] Polyhexylbiguanide hydrochloride was purchased from Shenzhen Hongda Gloria Co., Ltd., the CAS number is 32289-58-0, and the product trade name is CarlasoTM;

[0063] Alassi was purchased from Lewei (Taizhou) Pharmaceutical Chemical Co., Ltd., the CAS number is 22573-93-9 and the product catalog number is T1259.

[0064] Polyether F68 (the same compound as Pluronic F68 of BASF, Germany) was purchased from Jiangsu Haian Petrochemical Plant;

[0065] 904 was purchased from Germany BASF (BASF);

[0066] Ethylene glycol monobutyl ether (also known as ethylene glycol butyl ether) was purchased from Sinopharm Chemical Reagent Co., Ltd., and the product catalog number is 81008028;

[0067] Isopropanol was purchased from Sino...

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Abstract

The invention discloses a bactericide which comprises an alkyl biguanide bactericide, a polar organic solvent and water. The mass ratio of the alkyl biguanide bactericide to the polar organic solvent to the water is 0.01-2 to 2-50 to 50-98. The pH value of the bactericide ranges from 11.5 to 13.5. The alkyl biguanide bactericide is at least one of polyethyl methyl biguanide, alexidine and hydrochloride of the polyethyl methyl biguanide and the alexidine. The bactericide is high in bacteria killing speed, high in capacity and capable of killing bacterial spores. The bactericide is little in article surface corrosion, irritation and toxicity, and can serve as liquid medicine for disinfectant wet wipes. Surfaces are volatile and dry after the wet wipes are used, and accordingly alkalinity of a solution can be immediately neutralized by carbon dioxide in air. The bactericide can be used for disinfecting the article surfaces and human body surfaces and disinfecting the article surfaces and medical equipment, prevents spreading of microorganisms among people through contact of people and articles, can overcome the defects that existing products are high in human body irritation and low in bactericidal activity, and fills in gaps of international and domestic market.

Description

technical field [0001] The invention relates to a high-efficiency fungicide and its application. Background technique [0002] Disinfectants can be divided into sterilizers, high-efficiency disinfectants, medium-efficiency disinfectants and low-efficiency disinfectants according to their level of action. Sterilizers can kill all microorganisms to meet the sterilization requirements, including formaldehyde, glutaraldehyde, ethylene oxide, peracetic acid, hydrogen peroxide, chlorine dioxide and hypochlorous acid. The high-efficiency disinfectant can kill more than 99.9999% of all bacterial propagules (including mycobacteria), viruses, fungi, etc. (that is, the number of remaining bacteria is less than one millionth), and it also has a certain killing effect on bacterial spores . Intermediate-effect disinfectants only kill 99.9999% of bacterial propagules (including mycobacteria), viruses, fungi, etc., but have no killing effect on bacterial spores. Such fungicides include i...

Claims

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Application Information

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IPC IPC(8): A01N47/44A01N25/02A01P1/00A61K31/785A61K31/155A61K9/08A61P31/04A61P17/00
Inventor 俞致健
Owner NINGBO RUNZENG MEDICAL SCI & TECH