One-pot method for preparing 2-bromo-9,9-diphenylfluorene

Abstract

The invention relates to a one-pot method for preparing 2-bromo-9,9-diphenylfluorene and belongs to the technical field of organic synthesis. The method comprises steps shown in the specification. The reaction can be finished in one reactor, particularly for a chlorination reaction, intermediate products are not required to be separated out, a subsequent reaction of replacement of chlorine atoms with benzene rings is performed after a system reactant and a catalyst are directly added, the whole operation is simple, and the technology is reliable and suitable for enlargement; besides, by means of the used catalyst, side reactions can be effectively reduced, the product yield is increased to be higher than 90%, meanwhile, separation can be realized through filtration after the reaction due to the fact that the catalyst is a solid catalyst, and the after-treatment process is simplified.

Description

technical field

[0001] The invention belongs to the technical field of organic synthesis, and in particular relates to the preparation of 2-bromo-9,9-diphenylfluorene by a one-pot method. Background technique

[0002] Fluorene and its derivatives have the characteristics of a large conjugated system in the molecule, a rigid planar biphenyl structure, a wide energy gap, a high luminous efficiency, and easy modification of the structure, making them widely used in electroluminescent materials. , solar cell materials and other fields have a wide range of applications.

[0003] Dehydration reaction of tertiary alcohols with aromatic rings, Chang, ShunLi et al. (Journal of Organic Chemistry, 75(12), 4004-4013, 2010), Kim, BokYeong et al. (Repub.KoreanKongkaeTaehoKongbo, 2010006072), Seok, Hwan et al. (U.S.Pat.20090200928) and Lee, Seok-Jong et al. (U.S.Pat. 20040157084) respectively proposed trifluoromethanesulfonic acid and sulfuric acid as dehydrating agents. Trifluoromethane...

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