Unlock instant, AI-driven research and patent intelligence for your innovation.

Applications of gentiana macrophylla pall pill prescription in preparation of anti-aging drugs

A Qin Gentiana Pill, anti-aging technology, applied in the field of traditional Chinese medicine, can solve the problems of short life cycle, few anti-aging drugs, unclear function and curative effect of drugs, etc.

Inactive Publication Date: 2016-01-27
LANZHOU UNIVERSITY
View PDF2 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] However, the functions and curative effects of most drugs are not clear, and the product life cycle is short. Among them, there are very few anti-aging drugs suitable for premature aging patients, which cannot meet the urgent needs of this group of people at present.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Applications of gentiana macrophylla pall pill prescription in preparation of anti-aging drugs
  • Applications of gentiana macrophylla pall pill prescription in preparation of anti-aging drugs

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] Embodiment 1 Preparation of the water extract of Chinese medicine compound Qinjie pill

[0036] Zanthoxylum bungeanum 3g, Rehmannia glutinosa 3g, Roasted Inula 3g, Angelica 3g. Soak in distilled water for 20 minutes, then simmer and boil for 30 minutes, dilute the final volume to 100 mL, centrifuge, discard the precipitate, sterile filter the supernatant, and store it in a 4°C refrigerator for later use.

Embodiment 2

[0037] Example 2 Effects of traditional Chinese medicine compound Qinjie Wan on the lifespan of mutant progeria TK22 Caenorhabditis elegans

[0038] 1. Caenorhabditis elegans synchronization

[0039] The hatched adult worms of TK22 strain Caenorhabditis elegans were washed with M9 buffer into a 1.5mL centrifuge tube, left standing or centrifuged and discarded. Add 500μL of 1M NaOH and 500μL of 6.4% NaClO to each centrifuge tube, and put them in a vortexer. Lysis by shaking for about 7 min, centrifuged at 4000 rpm for 4 min, aspirate the supernatant, rinse twice with M9, add 500 μL of M9, incubate in a 20°C incubator, and inoculate it in an NGM solid Petri dish coated with OP50. Synchronized growth of C. elegans can be obtained by culturing at 20°C.

[0040] 2. Preparation of NGM plate containing Chinese medicine compound Qinjie pills

[0041] The extract of the Chinese medicine compound Qinqu Pill prepared in Example 1 is prepared according to the following method:

[0042]...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The present invention belongs to the field of traditional Chinese medicines, and relates to news of gentiana macrophylla pall pill prescription in pharmacy, particularly to applications of gentiana macrophylla pall pill prescription in preparation of anti-aging drugs. Aging is a natural process and mainly comprises that the body is subjected to hypofunction, the homeostasis capacity and the stress ability decrease, and the cells, the tissues and the organs of the body present degeneration in the structures and the functions along with the age increase; and based on the premature senescence populations, in order to fundamentally improve the life quality, the drug with effects of physical function improving and aging delaying is found so as to make the premature senescence population healthy age. The present invention provides the applications of the gentiana macrophylla pall pill prescription in preparation of the anti-aging drugs. The animal experiment results show that the gentiana macrophylla pall pill prescription can significantly prolong the lives of the premature senescence populations. The present invention provides the new uses of the gentiana macrophylla pall pill prescription, wherein the gentiana macrophylla pall pill prescription can be used for prevention of anti-aging drugs, and is expected to be developed into the new generation anti-aging drugs.

Description

technical field [0001] The invention relates to a new use of Qinjie pills in pharmacy, in particular to the application of Qinjiu pills in preparing anti-aging medicines, and belongs to the field of traditional Chinese medicine. Background technique [0002] Qinjiao Wan comes from the "Pu Ji Fang", which is composed of Zanthoxylum bungeanum, Rehmannia glutinosa, Zhixuanfuhua and Angelica dahurica. [0003] Aging is a natural process of life, mainly refers to the decline of body function with the increase of age, the decline of internal environment stabilization ability and stress ability, and the deterioration of the structure and function of the body's cells, tissues and organs. The consequences of aging are often aging-related diseases, leading to death. Faced with premature aging groups, in order to fundamentally improve their quality of life, it is necessary to find ways to improve physical function and delay aging, so that they can age healthily. [0004] However, the...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K36/804A61P39/06
Inventor 李红玉万凤奇支德娟李洋李莹辉陈晓雨
Owner LANZHOU UNIVERSITY