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Method of improving learning and memory in mammals

A memory and infant formula technology, applied in food science, drug combination, pharmaceutical formula, etc., can solve problems that do not affect the learning or memory behavior of mammals, and achieve the effect of improving learning and/or memory behavior

Inactive Publication Date: 2016-03-16
MJN U S HLDG LLC +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0017] While dietary administration of sialic acid has been reported for several purposes, there have been no reports of dietary supplementation with sialic acid affecting learning or memory behavior in mammals

Method used

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  • Method of improving learning and memory in mammals
  • Method of improving learning and memory in mammals
  • Method of improving learning and memory in mammals

Examples

Experimental program
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Effect test

reference example 1

[0067] This reference example illustrates nutritional components in a commercially available infant formula suitable for the addition of sialic acid that can be used in the present invention.

[0068] Table 1: Nutritional information for infant formula (Enfamil Lipil with iron)

[0069]

[0070]

[0071] The ingredients of this particular formula are: reduced mineral whey, skim milk, vegetable oils (palm olein, soybean oil, coconut oil, and high oleic sunflower oil), lactose, and less than 1% of: Mortierella alpine oil, cryptocodinium cohniii oil, vitamin A palmitate, vitamin D 3 , Vitamin E Acetate, Vitamin K 1 , Thiamine Hydrochloride, Vitamin B6 Hydrochloride, Vitamin B 12 , Niacinamide, Folic Acid, Calcium Pantothenate, Biotin, Sodium Ascorbate, Inositol, Calcium Chloride, Calcium Phosphate, Ferrous Sulfate, Zinc Sulfate, Manganese Sulfate, Copper Sulfate, Sodium Chloride, Sodium Citrate, Citric Acid Potassium, potassium hydroxide, sodium selenite, taurine, nucleo...

Embodiment 1

[0074] This example illustrates a specific combination of protein sources for a total sialic acid content of about 250 mg / L. The ingredients listed in Table 2 will be used to replace the protein component in the formula described in Table 1.

[0075] Table 2: Protein Source Composition A

[0076]

[0077] annotation : a. "SA" in the table refers to sialic acid.

[0078] b. CGMP refers to casein glycomacropeptide.

Embodiment 2

[0080] This example illustrates a specific combination of protein sources for a total sialic acid content of about 360 mg / L. The ingredients listed in Table 3 will be used to replace the protein component in the formula described in Table 1.

[0081] Table 3: Protein Source Composition B

[0082]

[0083] annotation : a. "SA" in the table refers to sialic acid.

[0084] b. CGMP refers to casein glycomacropeptide.

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Abstract

A method of improving learning and / or memory behavior in a mammal is described which involves administering to the mammal casein glycomacropeptide in an amount sufficient to improve learning and / or memory behavior in the mammal.

Description

[0001] The application date is March 28, 2006, the application number is 200680023512.3 (the international application number is PCT / US2006 / 011677), and the invention title is "method for improving the learning and memory of mammals". Apply. technical field [0002] The present invention relates to a method for improving the learning and / or memory behavior of mammals through food, more particularly, the present invention relates to a method for improving the learning and / or memory behavior of mammals by giving a food source of sialic acid . Background technique [0003] Breast milk and breastfeeding are recognized as the preferred means of feeding infants. One of the recognized benefits of breastfeeding is optimal mental development. For infants consuming infant formulas, substantial efforts have been made to provide formula compositions that support optimal mental development when compared to that observed in breastfed infants. [0004] Compared with other primates, adul...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23L33/17A23L33/00
CPCA23V2002/00A23V2200/30A23V2250/5424A23V2250/5488A23V2250/55A61K31/70A61K38/14A61K38/1709A23L33/185A61P25/28A23V2200/322A23V2250/54246A61K38/16A61K38/17
Inventor R.J.麦马洪B.王J.布兰德-米勒S.C.拉姆西
Owner MJN U S HLDG LLC
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