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Traditional Chinese medicine extract and application thereof in preparing drugs for treating hand-foot-mouth disease

A hand, foot and mouth disease and extract technology, which is applied in antiviral agents, pharmaceutical formulas, plant raw materials, etc., can solve the problems of unsatisfactory treatment effect and long treatment time of hand, foot and mouth disease, and achieve low cost of medicinal materials, no toxic side effects, pain relieving effect

Inactive Publication Date: 2016-03-30
冯悠慈
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

And the existing Chinese medicine for the treatment of children's hand, foot and mouth disease in the market, the treatment time of hand, foot and mouth disease is long, and therapeutic effect is unsatisfactory, therefore need to develop a kind of new Chinese medicine for children's hand, foot and mouth disease

Method used

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  • Traditional Chinese medicine extract and application thereof in preparing drugs for treating hand-foot-mouth disease

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] The traditional Chinese medicine combination extract is prepared from the following raw materials by weight: 13 parts of iron-coated gold, 11 parts of Yinchen, 8 parts of golden fruit olives, 16 parts of D.

[0019] The preparation steps of above-mentioned traditional Chinese medicine combination extract are as follows:

[0020] (1) Wash each raw material separately, and dry it in the natural environment to keep the water content of each raw material at 10-12%, weigh them according to the proportions, and pulverize them into 50-mesh medicinal materials with a pulverizer. well mixed;

[0021] (2) Add 10 times of the raw material to the above-mentioned mixed medicinal materials and soak them in water for 8 hours, extract the volatile oil by steam distillation, the extraction time is 4 hours, the extraction times are 3 times, and the volatile oil is collected to obtain the extract A;

[0022] (3) using the extract A obtained in step (2) with a volume concentration of 95% ...

Embodiment 2

[0025] The traditional Chinese medicine combination extract is prepared from the following raw materials in parts by weight: 15 parts of iron-coated gold, 10 parts of Yinchen, 9 parts of golden fruit olives, 14 parts of weeping pot grass, 10 parts of trichosanthin, and 12 parts of saffron.

[0026] The preparation steps of above-mentioned traditional Chinese medicine combination extract are as follows:

[0027] (1) Wash each raw material separately, and dry it in the natural environment to keep the water content of each raw material at 10-12%, weigh them according to the proportions, and pulverize them into 50-mesh medicinal materials with a pulverizer. well mixed;

[0028] (2) Add 11 times of the raw material to the above-mentioned mixed medicinal materials, soak them in water for 7 hours, and extract the volatile oil by steam distillation. The extraction time is 3.5 hours, and the extraction times are 4 times.

[0029] (3) using the extract A obtained in step (2) with a vol...

Embodiment 3

[0032] The traditional Chinese medicine combination extract is prepared from the following raw materials in parts by weight: 17 parts of iron-coated gold, 9 parts of Yinchen, 10 parts of golden fruit olives, 12 parts of weeping pot grass, 12 parts of trichosanthin, and 10 parts of saffron.

[0033] The preparation steps of above-mentioned traditional Chinese medicine combination extract are as follows:

[0034] (1) Wash each raw material separately, and dry it in the natural environment to keep the water content of each raw material at 10-12%, weigh them according to the proportions, and pulverize them into 50-mesh medicinal materials with a pulverizer. well mixed;

[0035] (2) Add 12 times of the raw material to the above-mentioned mixed medicinal materials and soak them in water for 8 hours, extract the volatile oil by steam distillation, the extraction time is 4 hours, and the extraction times are 3 to 3 times, and the volatile oil is collected to obtain the extract A;

[...

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Abstract

The invention discloses a traditional Chinese medicine extract and application thereof in preparing drugs for treating a hand-foot-mouth disease. The traditional Chinese medicine extract is prepared from roots of lineate supplejack, herba artemisiae scopariae, arrowshaped tinospora roots, herba sedi, radix trichosanthis and crocus sativus, the raw materials are cleaned and aired and mixed after being smashed, water is added for soaking, volatile oil is extracted through a steam distillation method, heating reflux extraction is conducted through ethanol, filtration is conducted after concentration is conducted, liquid medicine passes through macroporous adsorption resin, elution is conducted through an ethanol solution, concentration is conducted, the ethanol is removed, and the traditional Chinese medicine extract is obtained. According to the traditional Chinese medicine extract and the application thereof in preparing the drugs for treating the hand-foot-mouth disease, the traditional Chinese medicine formula is scientific, toxic and side effects do not exist, the treatment effect on the hand-foot-mouth disease is good, the children hand-foot-mouth disease can be effectively treated, pain of children is relieved, and the cost of medicinal materials is low.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine preparation, in particular to a traditional Chinese medicine combination extract and its application in the preparation of a medicine for treating hand, foot and mouth disease. Background technique [0002] Hand, foot and mouth disease (HFMD) is an acute infectious disease caused by enteroviruses. The clinical manifestations are generally more acute onset, with flu-like symptoms or gastrointestinal symptoms at the beginning of the onset, scattered herpes on the mucous membrane of the oral pharyngeal isthmus, maculopapular rashes and herpes on the hands, feet, buttocks or around the anus. In a few cases, meningitis, encephalitis, encephalomyelitis, pulmonary edema, and circulatory disorders may occur. It is mostly caused by enterovirus 71 (EV71) and Coxsackie A group 16 (CoxA16) infection, and the main causes of death are brainstem encephalitis and neurogenic pulmonary edema. ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/88A61P31/14
CPCA61K36/72A61K36/28A61K36/41A61K36/428A61K36/59A61K36/88A61K2236/17A61K2236/333A61K2236/39A61K2236/55A61K2300/00
Inventor 冯悠慈
Owner 冯悠慈