Method for extracting phenolic acid effective constituents of rhizome cimicifugae

Abstract

The invention discloses a method for extracting phenolic acid effective constituents of rhizome cimicifugae. The method includes the steps of taking and smashing rhizome-cimicifugae medicinal materials, adding a 55%-85%-ethyl alcohol solvent with the volume 6-14 times the weight of the rhizome-cimicifugae medicinal materials, and carrying out extracting 1-3 times, wherein each time of extracting lasts for 50-300 min; combining extracted solutions, and carrying out concentrating to obtain rhizome-cimicifugae extract containing the phenolic acid effective constituents. According to the extracting method, as factors such as the dissolvent ratio, the ethyl alcohol volume fraction, extracting time and the number of extracting times are analyzed and screened through a system, and the interaction relationships of the main influence factors such as the dissolvent ratio, the ethyl alcohol volume fraction and the extracting time are analyzed with a response surface analysis method on the basis of the screening results, and an optimal combination is screened out. An experimental result is verified to prove that according to the method, a process route is stable, operability is high, the content of the phenolic acid effective constituents in the extract obtained through preparing is high, and great application significance is achieved.

Description

technical field [0001] The invention relates to a method for extracting effective components of traditional Chinese medicine, in particular to a method for optimizing the extraction process of Cimicifuga japonicus by comprehensive weighted average response surface method. Background technique [0002] Cimicifuga is a traditional Chinese medicine in my country. It has the functions of expelling rash, clearing away heat and detoxification, and promoting Yang Qi. For wind-heat headache, toothache, aphtha, sore throat, impermeable measles, spots of impotence, prolapse of the anus, and prolapse of the uterus. Wide range of clinical applications and rich resources. Among them, the phenolic acid components have anti-oxidation, anti-inflammatory, anti-platelet aggregation, anti-tumor, lowering blood sugar and other effects through modern pharmacological research, and the clinical efficacy is remarkable. [0003] However, there is no unified standard for the processing and producti...

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Problems solved by technology

[0003] However, there is no uniform standard for the processing and production of Cimicifuga extract at present...

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