Pharmaceutical preparation for treating osteoporosis
A technology of pharmaceutical preparations and yams, which is applied in the direction of drug combinations, medical preparations containing active ingredients, bone diseases, etc., can solve the problems of many restrictions, long treatment cycles, and large side effects, and achieve the purpose of strengthening the body's integration and regulation, and treating Effective and easy to prepare
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Embodiment 1
[0026] A pharmaceutical preparation for osteoporosis, prepared from the following raw materials in parts by weight:
[0027] 40 parts of Radix Astragali, 40 parts of Nuxychia, 40 parts of Myrrh, 40 parts of Dipsacus, 35 parts of Salvia,
[0028] 35 parts of Duyiwei, 35 parts of Poria cocos, 35 parts of dandelion, 30 parts of licorice, 30 parts of coix seed,
[0029] 30 parts of Chinese yam, 28 parts of angelica, 28 parts of white peony root, 28 parts of Corydalis Corydalis, 28 parts of Citrus aurantium,
[0030] 25 parts of Daqing Ye, 25 parts of Mulberry Leaf, 25 parts of Aconite, 25 parts of Rubia, 20 parts of Liu Jinu,
[0031] 20 parts of Rhizoma Imperatae, 20 parts of Bamboo Leaf, 20 parts of Puhuang, 15 parts of Chuanxiong, 15 parts of Morus alba,
[0032] Epimedium 12 parts, Ligustrum lucidum 12 parts, Moutan bark 10 parts.
[0033] The preparation method of pharmaceutical preparation of the present invention is:
[0034] 1) Take each bulk drug and set aside;
[00...
Embodiment 2
[0041] functional experiment
[0042] Experimental animals 80 BABc mice, half male and half female, clean grade, weighing 20-22 g, were provided by the Animal Center of Municipal People's Hospital. They were randomly divided into 4 groups, 20 in each group, namely blank group, model control group, Example 1 group, and control drug group. Except for the blank group given normal saline, the other groups were given dexamethasone 1 mg / kg, injected once every three days, intramuscularly, and at the same time, combined with retinoic acid, 70 mg / kg per day, for three weeks for modeling .
[0043] Administration method: During the modeling period, except that the blank group and the model control group were given intragastric administration of equal volume of normal saline, the Example 1 group was given the drug of Example 1 of the present invention by intragastric administration, three times a day, and Gukang Capsule was used as the control drug. After three weeks of administration...
Embodiment 3
[0048] clinical information
[0049] 109 patients with osteoporosis were selected from the hospitalized cases in recent years. The diseased sites were: 22 cases of cervical spine, 54 cases of lumbar spine, 18 cases of knee joint, 7 cases of ankle joint, and 8 cases of calcaneus. Randomly divided into a treatment group and a control group. The medical history, condition, age, and sex of the selected cases in the treatment group and the control group were as similar as possible; the treatment group had 54 cases, and the control group had 55 cases. The two groups were comparable.
[0050] The treatment group was given the pharmaceutical composition prepared in Example 1 of the present invention, 0.3 grams each time, 3 times a day, one course of treatment a month, and took 2 courses of treatment continuously;
[0051] The control group was treated with conventional drug Gukang Capsules. Take orally, 3 capsules each time, 2 times a day, divided into morning and evening warm water ...
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