Porous bioactive glass bone repair material and preparing method thereof

A bioactive glass and bone repair technology, applied in tissue regeneration, medical science, prosthesis, etc., can solve the problems of low porosity of bioactive glass and affecting biological activity

Inactive Publication Date: 2016-06-01
HUBEI SHUANGXING PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the porosity of the prepared bioactive glass is not high, which affects its final bioactivity

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] A porous bioactive glass bone repair material

[0023] The parts by weight of the material composition consist of:

[0024] Na 2 O-CaO-SiO 2 -P 2 o 5 Bioactive glass powder 50 parts, urea 36 parts, polyethylene glycol PEG-40008 parts, starch 6 parts.

Embodiment 2

[0026] A porous bioactive glass bone repair material

[0027] The parts by weight of the material composition consist of:

[0028] Na 2 O-CaO-SiO 2 -P 2 o 5 Bioactive glass powder 50 parts, urea 36 parts, polyethylene glycol PEG-80008 parts, starch 6 parts.

Embodiment 3

[0030] A porous bioactive glass bone repair material

[0031] The parts by weight of the material composition consist of:

[0032] Na 2 O-CaO-SiO 2 -P 2 o 5 60 parts of bioactive glass powder, 22 parts of urea, 10 parts of polyethylene glycol PEG-4000, and 8 parts of starch.

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Abstract

The invention relates to a porous bioactive glass bone repair material and a preparing method thereof. The repair material is prepared from 50-65 parts of glass micro powder, 20-36 parts of urea, 8-18 parts of polyethylene glycol and 6-10 parts of starch. During preparation, the glass micro powder is used as a raw material, a urea, polyethylene glycol and starch mixture is used as a pore-forming agent, a small amount of a binding agent is added, and the porous bioactive glass bone repair material is prepared through compression molding of a performing machine and high-temperature calcination. The prepared repair material has uniform pores, is applied to bone defect repair and bone tissue loss regeneration, increases autogenous bone healing speed and improves bone repair efficiency.

Description

technical field [0001] The invention belongs to the field of bioactive materials, and in particular relates to porous bioactive glass for bone defect tissue repair, filling and tissue engineering repair and a preparation method thereof. Background technique [0002] Bioactive glass has good bioactivity and biocompatibility, and can be used as a material for human tissue repair and regeneration. In the clinical application of bone tissue repair and bone tissue engineering, it can promote the differentiation and proliferation of osteoblasts by activating some genes of osteoblasts, so as to have a good bone repair effect. However, traditional bioactive glass is a dense material with low strength and high brittleness, which affects its wide application in the field of bone repair. Medical research shows that the bioactive glass used for bone filling and repair needs a three-dimensional porous and interconnected pore structure of appropriate size to facilitate the penetration of...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C03C11/00C03C4/00A61L27/54A61L27/12A61L27/56
CPCC03C11/007A61L27/12A61L27/54A61L27/56A61L2430/02C03C4/0007
Inventor 廖书辉
Owner HUBEI SHUANGXING PHARMA CO LTD
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