Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Novel hemostatic material and preparation method thereof

A hemostatic material and a new type of technology, applied in the field of biomedical hemostatic materials, can solve the problems of limited wide application and unsatisfactory hemostatic effect, and achieve the effects of favorable structure stability, improved water absorption efficiency and strong water absorption ability.

Inactive Publication Date: 2016-06-15
广西达庆生物科技有限公司 +2
View PDF5 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] However, the hemostatic effect of these current technologies is not ideal, which limits their wide application in clinical practice.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0046] A novel hemostatic material, consisting of the following raw materials in weight percentage:

[0047] Microporous starch 20%

[0048] Collagen 20%

[0049] Hyaluronic Acid 20%

[0050] Puffball spore powder 40%.

[0051] The surface pore diameter of the microporous starch is 6-15 μm, and the porosity of the microporous starch is above 90%.

[0052] The collagen is a pharmaceutical grade powder with an average molecular weight of 500 daltons, and the hyaluronic acid is a pharmaceutical grade powder with an average molecular weight of 2000 daltons.

[0053] The puffball spore powder is the puffball spore powder obtained by peeling off the outer skin of the puffball, digging out the contents and sieving the spores, drying the spores at 110 degrees Celsius, crushing and passing through a sieve of more than 100 mesh.

[0054] The preparation method of described microporous starch comprises the following steps:

[0055] Step A, add water to 100g of starch to prepare star...

Embodiment 2

[0069] A novel hemostatic material, consisting of the following raw materials in weight percentage:

[0070] Microporous starch 40%

[0071] Collagen 20%

[0072] Hyaluronic Acid 20%

[0073] Puffball spore powder 20%.

[0074] The surface pore diameter of the microporous starch is 6-15 μm, and the porosity of the microporous starch is above 90%.

[0075] The collagen is a pharmaceutical-grade powder with an average molecular weight of 2000 Daltons, and the hyaluronic acid is a pharmaceutical-grade powder with an average molecular weight of 500 Daltons.

[0076] The puffball spore powder is the puffball spore powder obtained by peeling off the outer skin of the puffball, digging out the contents and sieving the spores, drying the spores at 120 degrees Celsius, and passing through a sieve with a mesh size of 100 or more after crushing.

[0077] The preparation method of described microporous starch comprises the following steps:

[0078] Step A, add water to 100g of starch...

Embodiment 3

[0094] A novel hemostatic material, consisting of the following raw materials in weight percentage:

[0095] Microporous starch 40%

[0096] Collagen 10%

[0097] Hyaluronic Acid 10%

[0098] Puffball spore powder 40%.

[0099] The surface pore diameter of the microporous starch is 6-15 μm, and the porosity of the microporous starch is above 90%.

[0100] The collagen is a pharmaceutical-grade powder with an average molecular weight of 1000 Daltons, and the hyaluronic acid is a pharmaceutical-grade powder with an average molecular weight of 1000 Daltons.

[0101] The puffball spore powder is the puffball spore powder obtained by peeling off the outer skin of the puffball, digging out the contents and sieving the spores, drying the spores at 130 degrees Celsius, and passing through a sieve with a mesh size of 100 or more after crushing.

[0102] The preparation method of described microporous starch comprises the following steps:

[0103] Step A, add water to 100g of starc...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
diameteraaaaaaaaaa
molecular weightaaaaaaaaaa
particle diameteraaaaaaaaaa
Login to View More

Abstract

The present invention relates to a biomedical hemostatic material, in particular to a novel hemostatic material and a preparation method thereof. It is composed of microporous starch, collagen, hyaluronic acid, and puffball spore powder. The microporous starch has the function of a molecular sieve and can be rapidly Absorbs water in the blood to form an "instant gel" that mechanically seals blood vessel openings; collagen can quickly combine with hemoglobin in the blood to form a hemostatic clot, and collagen can penetrate into new tissues and act as a barrier for cell growth. Scaffold; hyaluronic acid can instantly absorb water in the blood to form a hydrogel, thereby blocking bleeding; puffball spore powder stores a large number of microporous fibers, which can quickly absorb water in the blood, and can mechanically seal blood vessel breaks and Capillaries ooze blood, and these four together form a physical barrier, which can isolate the wound, play the role of anti-adhesion and immediate hemostasis. The invention is used for hemostasis of various wounds and wounds of fresh tissues, hemorrhage of small blood vessels and bleeding areas, and prevention of adhesion.

Description

technical field [0001] The invention relates to the technical field of biomedical hemostatic materials, in particular to a novel hemostatic material and a preparation method thereof. Background technique [0002] Hemostasis is an important link in the operation of various departments in the hospital, and plays a considerable role in the success of the operation and the safety of the patient. The normal hemostasis mechanism mainly includes three aspects: the contraction of small blood vessels, the activation of platelets and the activation of the coagulation system. Among them, the contraction of small blood vessels is the earliest response to hemostasis after trauma. After the blood vessels are damaged, the smooth muscles of the blood vessels constrict the blood vessels and slow down the blood flow through axon reflex, which is beneficial to blood coagulation and hemostasis. Platelets have the physiological function of adhering to the surface of wounds and foreign bodies, a...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61L24/10A61L24/08A61L24/00
CPCA61L24/102A61L24/0015A61L24/08A61L2300/232A61L2300/236A61L2300/252A61L2300/30A61L2300/418A61L2400/04C08L3/02C08L5/08
Inventor 梁奕福
Owner 广西达庆生物科技有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com