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Composition having function of reducing activity of periodontal pathogens as well as preparation method and application of the composition

A technology of pathogenic bacteria and composition, which is applied in the field of composition and its preparation and application that can reduce the activity of periodontal pathogenic bacteria, and can solve problems such as irritation, damage to the composition of oral flora, and swallowing

Active Publication Date: 2016-07-20
云南白药天颐茶品有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, long-term use of drugs will inevitably have many adverse reactions, and the adverse reactions of some traditional Chinese medicines are even more unclear
Mouthwashes whose active ingredients are monomeric compounds often contain irritating ingredients, and swallowing will inevitably occur when using them. At the same time, long-term use will destroy the composition of oral flora, leading to more serious consequences

Method used

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  • Composition having function of reducing activity of periodontal pathogens as well as preparation method and application of the composition
  • Composition having function of reducing activity of periodontal pathogens as well as preparation method and application of the composition

Examples

Experimental program
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Effect test

Embodiment 1

[0032] The tableted candy that reduces the active effect of periodontal pathogenic bacteria described in the present embodiment, the specific preparation method is as follows:

[0033] 1. Preparation of honeysuckle extract: soak honeysuckle in 4 times the weight of 50% ethanol aqueous solution with a pH of 2.5, soak at 30°C for 18 hours, filter the obtained extracts with 200 mesh and 5um filter bags, and dry the filtrate under reduced pressure. Obtain honeysuckle extract after crushing;

[0034] 2. Preparation of Luo Han Guo extract: take Luo Han Guo, add 6 times the weight of water, extract at 75°C for 0.5 hours, extract twice, and obtain the extract after centrifugation at 4000-6000 rpm, and then use a 0.2um ultrafiltration membrane. Filtration, the filtrate is concentrated by reverse osmosis and then dried under reduced pressure or spray-dried to obtain the Luo Han Guo extract;

[0035] 3. Preparation of green tea extract: take green tea, add 5 times the weight of water, e...

Embodiment 2

[0039] The mouthwash that reduces periodontal pathogenic bacteria described in the present embodiment, concrete preparation method is as follows:

[0040] 1. Preparation of honeysuckle extract: soak honeysuckle in 8 times the weight of 75% ethanol aqueous solution with a pH of 2.5, soak at 60°C for 20 hours, and filter the obtained extracts with 200 mesh and 5um filter bags respectively, and dry the filtrate under reduced pressure. Obtain honeysuckle extract after crushing;

[0041] 2. Preparation of Luo Han Guo extract: Take Luo Han Guo, add 12 times the weight of water, extract at 90°C for 1 hour, extract once, and the obtained extract is centrifuged at 6000 rpm, and then filtered with a 0.5um ultrafiltration membrane. After the filtrate is concentrated by reverse osmosis, it is dried under reduced pressure or spray-dried to obtain the Luo Han Guo extract;

[0042] 3. Preparation of green tea extract: Take green tea, add 15 times the weight of water, extract at 95°C for 1 h...

Embodiment 3

[0046] The health food that reduces periodontal pathogenic bacteria described in the present embodiment, concrete preparation method is as follows:

[0047] 1. Preparation of honeysuckle extract: soak honeysuckle in 6 times the weight of 65% ethanol aqueous solution with a pH of 2.5, soak for 30 hours at room temperature, and filter the obtained extracts with 200 mesh and 5um filter bags respectively, and dry the filtrate under reduced pressure and pulverize After obtaining honeysuckle extract;

[0048] 2. Preparation of Luo Han Guo extract: take Luo Han Guo, add 6-12 times the weight of water, extract at 75-90 ° C for 0.5-1 hour, extract 1-2 times, and obtain the extract after centrifugation at 4000 rpm. um ultrafiltration membrane for filtration, and the filtrate is concentrated by reverse osmosis and then dried under reduced pressure or spray dried to obtain the extract of Luo Han Guo;

[0049] 3. Preparation of green tea extract: Take green tea, add 12 times the weight of...

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Abstract

The invention discloses a composition having a function of reducing activity of periodontal pathogens. The composition consists of a honeysuckle extract, a fructus momordicae extract, a green tea extract, lactobacillus paracasei and fructus phyllanthi powder. The preparation method comprises the following steps: preparing the honeysuckle extract, the fructus momordicae extract and the green tea extract in a separated mode, and preparing the fructus phyllanthi powder; and uniformly mixing the prepared honeysuckle extract, fructus momordicae extract, green tea extract and fructus phyllanthi powder with lactobacillus paracasei, so that the composition has the function of reducing the activity of the periodontal pathogens is obtained. The invention discloses application of the composition in preparing foods or health care foods and application of the composition in preparing daily chemical products for oral care. The composition disclosed by the invention can be prepared into various foods and oral care articles, so that the function of effectively reducing the activity of the periodontal pathogens is achieved when people eat the foots and accept oral care, and the teeth of the people are fully protected. The product disclosed by the invention, even being eaten for a long time or taken as tea, is free from adverse reactions and side effects.

Description

technical field [0001] The present invention relates to a kind of composition that combines traditional Chinese medicine and Lactobacillus paracasei, specifically a kind of composition that can reduce the activity of periodontal pathogenic bacteria and its preparation method, and the present invention also relates to this composition in health food or Oral cleaning and nursing daily chemical products. Background technique [0002] Oral hygiene is getting more and more attention. From enamel, dentin to gums, as well as the cleanliness of the entire oral cavity, oral odor, etc. all directly affect the oral health status. According to the daily oral care habits of ordinary consumers, they mainly clean their mouths by brushing their teeth, and some consumers are accustomed to using mouthwash. In addition, a small number of consumers will regularly undergo specialized outpatient treatment, such as teeth cleaning, polishing and other treatments . Studies have shown that many ora...

Claims

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Application Information

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IPC IPC(8): A61K36/82A61P1/02A61P31/04A23L33/00A61K8/99A61K8/97A61Q11/00A61K35/747
CPCA23V2002/00A61K8/97A61K8/99A61K35/747A61K36/355A61K36/42A61K36/47A61K36/82A61K2236/331A61K2236/333A61K2236/51A61K2236/53A61Q11/00A61K2300/00A23V2250/21A23V2250/206
Inventor 姚坤华黄卫东韦建荣王丽娜戴银装李茜
Owner 云南白药天颐茶品有限公司
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