Sea cucumber fat-soluble extract, lip balm containing the extract and preparation method

A fat-soluble extract, extract technology, applied in skin care preparations, pharmaceutical formulations, cosmetic preparations, etc., can solve long-term problems, achieve low temperature, good biocompatibility, and simple preparation methods

Active Publication Date: 2018-08-28
YANTAI HUAKANG SEAFOOD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

All kinds of lipsticks currently on the market are mainly moisturizing and moisturizing, and it is better to prevent chapped lips. However, it takes a long time to repair chapped lips, and it repairs the self-repairing function of the main skin.
At present, there are few lip balms with lip repair as the main ingredient on the market

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] Embodiment 1: the extraction of sea cucumber fat-soluble extract

[0038]Rinse 1 kg of fresh sea cucumber with clean water quickly, cut open the abdomen, remove viscera, gonads, sediment, etc., take its body wall, wash the body wall with tap water and double distilled water respectively, cut it into pieces, soak in double distilled water for about 0.5h, then try to remove water, weighed. Add about 8 times the amount (mass ratio) of double distilled water to the shredded sea cucumber body wall, and use a disperser to homogenize to obtain a sea cucumber homogenate. Put the above sea cucumber homogenate in a constant temperature water bath at 50°C, adjust the pH to 2.0-2.5 with 6mol / L HCl solution, add a certain amount of pepsin according to 0.4% of the weight of the sea cucumber, then adjust the pH to 2.3, and bathe the enzyme in a constant temperature water bath at 50°C Solution for 5h, keep stirring, and keep the pH in the range of 2.0-2.5. After pepsin enzymatic hydr...

Embodiment 2

[0040] Embodiment 2: the extraction of sea cucumber fat-soluble extract

[0041] Rinse 5 kg of fresh sea cucumber with clean water quickly, cut open the abdomen, remove viscera, gonads, sediment, etc., take its body wall, wash the body wall with tap water and double distilled water respectively, cut it into pieces, soak in double distilled water for about 0.5h, then try to remove water, weighed. Add about 8 times the amount (mass ratio) of double distilled water to the shredded sea cucumber body wall, and use a disperser to homogenize to obtain a sea cucumber homogenate. Put the above sea cucumber homogenate in a constant temperature water bath at 50°C, adjust the pH to 2.0-2.5 with 6mol / L HCl solution, add a certain amount of pepsin according to 0.4% of the weight of the sea cucumber, then adjust the pH to 2.3, and bathe the enzyme in a constant temperature water bath at 50°C Solution for 5h, keep stirring, and keep the pH in the range of 2.0-2.5. After pepsin enzymatic hyd...

Embodiment 3

[0044] Rinse 5 kg of fresh sea cucumber with clean water quickly, cut open the abdomen, remove viscera, gonads, sediment, etc., take its body wall, wash the body wall with tap water and double distilled water respectively, cut it into pieces, soak in double distilled water for about 0.5h, then try to remove water, weighed. Add about 9 times the amount (mass ratio) of double distilled water to the shredded sea cucumber body wall, and use a disperser to homogenize to obtain a sea cucumber homogenate. Put the above sea cucumber homogenate in a constant temperature water bath at 50°C, adjust the pH to 2.0-2.5 with 6mol / L HCl solution, add a certain amount of pepsin according to 0.35% of the weight of the sea cucumber, and then adjust the pH to 2.3, and bathe the enzyme in a constant temperature water bath at 50°C Solution for 4.5h, keep stirring, and keep the pH in the range of 2.0-2.5. After pepsin enzymatic hydrolysis, put the enzymatic hydrolysis solution in a constant tempera...

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PUM

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Abstract

The invention discloses a fat-soluble extract of a sea cucumber, a lipstick containing the extract and preparation methods of the fat-soluble extract and the lipstick containing the extract. The preparation method of the extract comprises the following steps of (1), preprocessing the sea cucumber, so as to obtain a homogenate of the sea cucumber; (2), enzymolysis: carrying out enzymolysis on the homogenate of the sea cucumber in the step (1) through pepsase and trypsase in sequence, so as to obtain an enzymatic hydrolysate; (3), regulating the pH (potential of Hydrogen) of the enzymatic hydrolysate to be 6.8 to 7.2, taking a supernatant fluid to carry out concentration, then adding sesame oil in a set proportion into the supernatant fluid, agitating and extracting an obtained mixture for several times, carrying out centrifugation after extraction, and merging supernatant fluids to obtain the fat-soluble extract of the sea cucumber. The lipstick containing the extract, which is provided by the invention, has a better rehabilitation effect, and the phenomenon that a lip becomes dry and chapped can be removed within a short time through rehabilitation.

Description

technical field [0001] The invention relates to a preparation method and application of a sea cucumber fat-soluble extract and a lipstick, in particular to a lip balm containing a sea cucumber fat-soluble extract and a preparation method thereof. Background technique [0002] Sea cucumbers (Sea cucumbers, holothurians) belong to the class Holothurioidea of ​​the phylum Echinodermata, and are important marine invertebrates. In the world, the medicinal use of sea cucumbers was first recorded in my country's "Compendium of Materia Medica Supplements", which records that sea cucumbers have the medicinal value of tonifying the kidney meridian, benefiting the essence, eliminating phlegm and saliva, urinating, generating blood and strengthening yang, and treating ulcer reproduction. In addition, a large number of studies have shown that sea cucumber is a high-protein, low-fat and low-cholesterol seafood. Sea cucumber hydrolyzate also contains glycine, glutamic acid, aspartic acid,...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/98A61Q19/00A61Q19/08
CPCA61K8/987A61Q19/00A61Q19/08
Inventor 宋淑亮张娥吉爱国
Owner YANTAI HUAKANG SEAFOOD
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