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Traditional Chinese medicine composition for treating hyperthyroidism and preparation method thereof

A composition and technology of traditional Chinese medicine, applied in the field of medicine, can solve the problems of large side effects, recurrence, etc., achieve the effects of small side effects, simple raw materials, and improved therapeutic effect

Inactive Publication Date: 2016-08-17
INST OF BASIC RES & CLINICAL MEDICINE CHINA ACAD OF CHINESE MEDICAL SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, the commonly used drugs for the treatment of hyperthyroidism include methimazole, levothyroxine, and propylthiouracil. These drugs can quickly balance the thyroid content in the body, but they have relatively large side effects. Tends to relapse when not taken

Method used

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  • Traditional Chinese medicine composition for treating hyperthyroidism and preparation method thereof
  • Traditional Chinese medicine composition for treating hyperthyroidism and preparation method thereof
  • Traditional Chinese medicine composition for treating hyperthyroidism and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] A traditional Chinese medicine composition for treating hyperthyroidism, comprising the following traditional Chinese medicine raw materials in parts by mass: 5 parts of Prunella vulgaris extract and 7 parts of Schisandra chinensis extract.

[0023] A traditional Chinese medicine composition for treating hyperthyroidism, the preparation method is: after uniformly mixing the extract of Prunella vulgaris and the extract of Schisandra chinensis, it is prepared into any oral dosage form mentioned in pharmacy.

[0024] The extraction method of described Prunella vulgaris extract is:

[0025] (1) Pulverize Prunella vulgaris, add 8 times the mass of 90% ethanol for leaching at 60°C for 3 times, each time for 20 minutes, and combine the three extracts;

[0026] (2) decompressing the combined extracts to reclaim ethanol until there is no alcohol smell to obtain a liquid extract;

[0027] (3) Dissolving the liquid extract in distilled water of equal volume to obtain an aqueous s...

Embodiment 2

[0036] A traditional Chinese medicine composition for treating hyperthyroidism, comprising the following traditional Chinese medicine raw materials in parts by mass: 7 parts of Prunella vulgaris extract and 11 parts of Schisandra chinensis extract.

[0037] A traditional Chinese medicine composition for treating hyperthyroidism, the preparation method is: after uniformly mixing the extract of Prunella vulgaris and the extract of Schisandra chinensis, it is prepared into any oral dosage form mentioned in pharmacy.

[0038] The extraction method of described Prunella vulgaris extract is:

[0039] (1) Pulverize Prunella vulgaris, add 10 times the mass of 90% ethanol for leaching at 65°C for 3 times, each time for 25 minutes, and combine the three extracts;

[0040] (2) decompressing the combined extracts to reclaim ethanol until there is no alcohol smell to obtain a liquid extract;

[0041] (3) Dissolving the liquid extract in distilled water of equal volume to obtain an aqueous...

Embodiment 3

[0050] A traditional Chinese medicine composition for treating hyperthyroidism, comprising the following traditional Chinese medicine raw materials in parts by mass: 9 parts of Prunella vulgaris extract and 15 parts of Schisandra chinensis extract.

[0051] A traditional Chinese medicine composition for treating hyperthyroidism, the preparation method is: after uniformly mixing the extract of Prunella vulgaris and the extract of Schisandra chinensis, it is prepared into any oral dosage form mentioned in pharmacy.

[0052] The extraction method of described Prunella vulgaris extract is:

[0053] (1) Pulverize Prunella vulgaris, add 12 times the mass of 90% ethanol for extraction at 70°C for 3 times, each time for 30 minutes, and combine the three extracts;

[0054] (2) decompressing the combined extracts to reclaim ethanol until there is no alcohol smell to obtain a liquid extract;

[0055] (3) Dissolving the liquid extract in distilled water of equal volume to obtain an aqueo...

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Abstract

The invention discloses a traditional Chinese medicine composition for treating hyperthyroidism. The traditional Chinese medicine composition is composed of common selfheal spike extract and Chinese magnoliavine fruit extract and may be made into any pharmaceutically acceptable oral dosage form, including a tablet, a capsule, a granule, a pill and syrup. According to the invention, the raw materials are simple; cost is reduced compared with other compositions for treating hyperthyroidism; a specific traditional Chinese medicine extraction method is employed, so the recovery rates of effective components in the traditional Chinese medicines are increased; and the traditional Chinese medicine composition has improved treatment effect and small toxic and side effect.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition for treating hyperthyroidism and a preparation method thereof, belonging to the field of medicine. Background technique [0002] Hyperthyroidism (hereinafter referred to as hyperthyroidism) is a group of common endocrine diseases caused by excessive secretion of thyroid hormone caused by various reasons. The main clinical manifestations are polyphagia, weight loss, fear of heat, hyperhidrosis, palpitations, agitation and other hypermetabolic syndromes, as well as varying degrees of goiter, exophthalmos, hand tremors, and tibial vascular murmurs. Hyperthyroid crisis, coma and even life-threatening. The clinical morbidity rate is relatively high, and there is a trend of gradually increasing, which has attracted more and more attention of clinical workers. [0003] At present, the commonly used drugs for the treatment of hyperthyroidism include methimazole, levothyroxine, and propylthio...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/79A61K36/57A61P5/16
CPCA61K36/79A61K36/536A61K36/57A61K2236/333A61K2236/39A61K2236/51A61K2236/55A61K2300/00
Inventor 吕爱平张戈吕诚赵宁王茂林姜淼何小鹃谭勇张弛李立白菁安鲁军党蕾
Owner INST OF BASIC RES & CLINICAL MEDICINE CHINA ACAD OF CHINESE MEDICAL SCI
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