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Hemostasis Chinese herb preparation for general surgery department and preparing method and application thereof

A traditional Chinese medicine preparation and general surgery technology, applied in the field of medicine, can solve the problems of less than 70% cure rate, low drug effective rate, and long healing time, and achieve the effects of no toxic side effects, significant hemostatic effect, and low cost

Inactive Publication Date: 2016-08-17
肖均财
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although the existing hemostatic drugs have certain effects, their effects are not ideal, the healing time is long, the incision healing is delayed, and some incision infections can only heal after prolonging to 2-3 months, and the effective rate of the drugs is low, generally less than 78%. %, the cure rate is less than 70%, and it is easy to leave scars

Method used

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  • Hemostasis Chinese herb preparation for general surgery department and preparing method and application thereof

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Experimental program
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Effect test

Embodiment 1

[0021] In the embodiment of the present invention, a hemostatic traditional Chinese medicine preparation for general surgery is composed of the following raw materials in parts by weight: 20 parts of fresh cortex, 12 parts of Aesculus chinensis, 2 parts of Imperata rhizome, and 5 parts of antipodal leaves.

[0022] Grind the fresh cortex and Aesculus aesculata, pass through a 100-mesh sieve, add ethanol with a volume concentration of 80% that is 7 times the mass of the two, stir at 50°C for 50 minutes, and then carry out microwave extraction. The microwave extraction power is 700W. Microwave extraction was performed twice, and the microwave extraction time was 9 min each time. The extracts were combined and concentrated to 30% of the original volume to obtain an extract concentrate. Crush the rhizome of Imperata corydalis and the pair of leaves, pass through a 80-mesh sieve, freeze at -20°C for 15 minutes, and then freeze at -10°C for 40 minutes; put the frozen roots of Imperat...

Embodiment 2

[0024] In the embodiment of the present invention, a hemostatic traditional Chinese medicine preparation for general surgery is composed of the following raw materials in parts by weight: 30 parts of fresh cortex, 20 parts of Aesculus chinensis, 8 parts of Imperata rhizome, and 13 parts of antipodal leaves.

[0025] Grind the white fresh skin and Aesculus chinensis, pass through a 150-mesh sieve, add 80% ethanol that is 8 times the weight of the two, stir at 55°C for 60 minutes, and then perform microwave extraction. The power of microwave extraction is 800W, and microwave extraction is performed twice. , each microwave extraction time is 10min, the combined extracts are concentrated to 40% of the original volume to obtain the extract concentrate. Crush the rhizome of Imperata corydalis and the pair of leaves, pass through a 120-mesh sieve, freeze at -20°C for 20 minutes, then freeze at -10°C for 50 minutes; put the frozen roots of Imperata cottage and the pair of leaves into a...

Embodiment 3

[0027] In the embodiment of the present invention, a hemostatic traditional Chinese medicine preparation for general surgery is composed of the following raw materials in parts by weight: 22 parts of fresh cortex, 14 parts of Aesculus aesculata, 4 parts of Imperata rhizome, and 7 parts of antipodal leaves.

[0028] Grind the fresh cortex and Aesculus aesculata, pass through a 150-mesh sieve, add 80% ethanol that is 8 times the mass of the two, stir at 52°C for 55 minutes, and then perform microwave extraction. The power of the microwave extraction is 800W, and the microwave extraction is performed twice. , each microwave extraction time is 10min, the combined extracts are concentrated to 35% of the original volume to obtain the extract concentrate. Crush the rhizome of Imperata corydalis and the pair of leaves, pass through a 120-mesh sieve, freeze at -20°C for 20 minutes, and then freeze at -10°C for 45 minutes; put the frozen roots of Imperata cottage and the pair of leaves i...

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Abstract

The invention discloses a hemostasis Chinese herb preparation for the general surgery department and a preparing method and application thereof. The hemostasis Chinese herb preparation for the general surgery department is prepared from, by weight, 20-30 parts of cortex dictamni, 12-20 parts of paris polyphylla, 2-8 parts of cogongrass rhizome and 5-13 parts of alate pteracanthus leaves. Cortex dictamni and paris polyphylla are smashed and screened, 80% ethyl alcohol is added, heating is carried out, microwave extracting is carried out, and extract liquor is mixed and concentrated to obtain extracted concentrated liquor; cogongrass rhizome and the alate pteracanthus leaves are smashed, screened and frozen, deionized water is added, and heat preservation, heating, boiling, filtering and concentrating are carried out to prepare concentrated liquor; the extracted concentrated liquor and the boiled concentrated liquor are mixed, and heating stirring is carried out to prepare extract to obtain the Chinese herb preparation. The prepared Chinese herb preparation has the advantages of being remarkable in hemostasis effect, taking effect fast, resisting bacteria and being free of toxic and side effects, no scar exists after healing, cost is low, and the preparation is suitable for industrialized production, and can be widely applied to various kinds of internal and external hermorrhage, surgical hemostasis and the like.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to a traditional Chinese medicine preparation for hemostasis in general surgery and its preparation method and application. Background technique [0002] Trauma bleeding and bleeding during surgery are common symptoms in general surgery. Blood loss will reduce the fluid in the blood vessels and cause hypotension, which will reduce the oxygen supply of the body tissues and damage the body. Mass blood loss may even cause serious consequences such as hemorrhagic shock, directly endangering human life. Therefore, in trauma treatment, surgical operation and other occasions, hemostasis operation must be performed on the bleeding site at the first time. And with the improvement of surgical operation level and surgical treatment coverage in our country, and the shortage of organ transplantation, procoagulant and hemostatic drugs have become indispensable drugs. At present, hemostatic dru...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/899A61P7/04
CPCA61K36/75A61K9/0014A61K36/11A61K36/19A61K36/896A61K36/899A61K2236/331A61K2236/333A61K2236/39A61K2236/51A61K2300/00
Inventor 肖均财
Owner 肖均财