Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Preparation method of nano-silver hybrid sericin porous gel antibacterial material, product and application thereof

An antibacterial material and nano-silver technology, applied in the direction of resisting vector-borne diseases, transportation and packaging, metal processing equipment, etc., to achieve the effects of simple operation, good application prospects, and obvious bacteriostatic effect.

Active Publication Date: 2016-08-31
SOUTHWEST UNIVERSITY
View PDF5 Cites 12 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Because nano silver has the characteristics of broad-spectrum sterilization, strong sterilization, long-lasting sterilization, and no drug resistance, nano silver is widely used in the medical field, such as antibacterial sprays, antibacterial bandages, cardiovascular implant coatings, catheterization, etc. Tube coatings, dental material coatings, medical device coatings, antibacterial textiles, etc., but there is no report on the surface modification of sericin with nano silver

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Preparation method of nano-silver hybrid sericin porous gel antibacterial material, product and application thereof
  • Preparation method of nano-silver hybrid sericin porous gel antibacterial material, product and application thereof
  • Preparation method of nano-silver hybrid sericin porous gel antibacterial material, product and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] The preparation method of nano-silver hybrid sericin porous gel antibacterial material comprises the following steps:

[0033] (1) Preparation of sericin powder: Take 10g of silkworm cocoons and cut them into small pieces, place them in an autoclave (120°C, 0.1Mpa) for 20min under high pressure according to the bath ratio of 1:30, wring out the silk after high pressure, and use Filter through gauze to obtain sericin solution, freeze at -80°C for 2 hours, and place in a freeze dryer for 24 hours to obtain sericin powder;

[0034](2) Preparation of sericin porous gel: redissolve the sericin powder obtained in step (1) in hot water (80° C.) to a solution of 8% (wt), pour it into a mold, and then place it in a refrigerator at -20° C. Freeze for 2 hours, take it out and allow it to reabsorb water, put it in a -20°C refrigerator for 2 hours, and then place it in a freeze dryer for 12 hours to obtain sericin porous gel;

[0035] (3) Preparation of nano-silver hybrid sericin p...

Embodiment 2

[0037] The preparation method of nano-silver hybrid sericin porous gel antibacterial material comprises the following steps:

[0038] (1) Preparation of sericin powder: Take 10g of silkworm cocoons and cut them into small pieces, place them in an autoclave (120°C, 0.1Mpa) for 30min under high pressure according to the bath ratio of 1:30, wring out the silk after high pressure, and use Filter through gauze to obtain sericin solution, freeze at -80°C for 2 hours, and place in a freeze dryer for 24 hours to obtain sericin powder;

[0039] (2) Preparation of sericin porous gel: redissolve the sericin powder obtained in step (1) in hot water (80° C.) to a solution of 8% (wt), pour it into a mold, and then place it in a refrigerator at -20° C. Freeze for 2 hours, take it out and allow it to reabsorb water, put it in a -20°C refrigerator for 2 hours, and then place it in a freeze dryer for 12 hours to obtain sericin porous gel;

[0040] (3) Preparation of nano-silver hybrid sericin ...

Embodiment 3

[0042] The preparation method of nano-silver hybrid sericin porous gel antibacterial material comprises the following steps:

[0043] (1) Preparation of sericin powder: Take 10g of silkworm cocoons and cut them into small pieces, place them in an autoclave (120°C, 0.1Mpa) for 20min under high pressure according to the bath ratio of 1:30, wring out the silk after high pressure, and use Filter through gauze to obtain sericin solution, freeze at -80°C for 2 hours, and place in a freeze dryer for 24 hours to obtain sericin powder;

[0044] (2) Preparation of sericin porous gel: redissolve the sericin powder obtained in step (1) in hot water (80° C.) to a solution of 8% (wt), pour it into a mold, and then place it in a refrigerator at -20° C. Freeze for 2 hours, take it out and allow it to reabsorb water, put it in a -20°C refrigerator for 2 hours, and then place it in a freeze dryer for 12 hours to obtain sericin porous gel;

[0045] (3) Preparation of nano-silver hybrid sericin ...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a preparation method of a nano-silver hybrid sericin porous gel antibacterial material, a product and application thereof. The preparation method includes: extracting sericin from silk, and acquiring sericin powder by freeze drying; re-dissolving the sericin powder, then performing refrigeration to prepare sericin hydrogel, and conducting freeze drying to obtain loose and porous sericin gel, then immersing the sericin porous gel in an AgNO3 solution, conducting in situ synthesis of nano-silver on the surface of the sericin porous gel by means of ultraviolet radiation reduction, thus obtaining the nano-silver hybrid sericin porous gel antibacterial material. Growth curve determination and inhibition zone analysis show that the nano-silver hybrid sericin porous gel antibacterial material prepared by the method provided by the invention has a significant inhibitory effect on growth of escherichia coli and staphylococcus aureus. The method provided by the invention has the characteristics of simple operation, mild condition, green and environmental protection, and is expected to prepare antibacterial materials for the field of biomedical materials.

Description

technical field [0001] The invention belongs to the field of biological materials, in particular to a method for preparing a nano-silver hybrid sericin porous gel antibacterial material, and also to the nano-silver hybrid sericin porous gel antibacterial material and nano-silver hybrid sericin prepared by the method Application of porous gel antibacterial materials. Background technique [0002] Silk is composed of two parts: fibroin in the inner layer and sericin in the outer layer. Sericin plays a role in lubricating the flow of silk fibroin in silkworms, protecting and adhering silk fibroin in cocoon silk, and in the process of silk production, reeling and gray silk refining. Gray silk also plays a protective role, but due to the needs of silk making and textile technology, most of sericin is removed in the spinning process, so there is a large amount of sericin in the wastewater discharged by silk making and silk manufacturers. For a long time, due to insufficient unde...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61L15/32A61L15/18A61L15/42A61L15/44B22F9/24B22F1/00
CPCA61L15/18A61L15/32A61L15/42A61L15/44B22F9/24A61L2300/404A61L2300/104B22F1/054Y02A50/30
Inventor 何华伟陶刚王叶菁赵萍夏庆友
Owner SOUTHWEST UNIVERSITY
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com