3 results about "Cardiovascular implant" patented technology

The invention relates to a cardiovascular implant device for directing flow. A cardiovascular implant device includes an annular body, one or more anchoring members, and a diversion assembly. The annular body includes a central flow tube extending from an inflow end to an outflow end and a flow path extending through the central flow tube. The one or more anchoring members extend outwardly from the annular body and are configured to secure the cardiovascular implant device to a tissue wall. The diversion assembly is positioned to align blood flow out of the cardiovascular implant device with a natural flow pattern of blood in the right atrium such that the blood flow out of the cardiovascular implant device is combined with the natural flow pattern of blood in the right atrium.

The invention relates to the technical field of biomedical materials, and particularly discloses a laser surface treatment method and application of a magnesium alloy wire. The invention discloses a laser surface treatment method of a magnesium alloy wire. The surface of the magnesium alloy wire is treated by adopting a laser surface treatment technology with the following process parameters: the scanning speed is 5-15 mm / s, the wavelength is 1050-1080 nm, the pulse width is 1 * 10 <-9 >-3 * 10 <-9 > s, the power is 5-8 W, the frequency is 18000-22,000 Hz, the light spot size is 1 / e2, the diameter is 150-175 microns, and the pulse energy density is 2.0-3.0 J / cm < 2 >. According to the scheme, in-situ tissue reconstruction is carried out through a laser surface treatment method, so that the corrosion resistance of the magnesium alloy is greatly enhanced, the reliability of the magnesium alloy wire in a cardiovascular implant is improved, the service life of the magnesium alloy wire in the cardiovascular implant is prolonged, meanwhile, the green manufacturing requirement is met, and the defects of a traditional method in the degradation control aspect are overcome.

This invention relates to a recombinant hirudin fusion protein with collagen affinity, its preparation method, and its applications. The fusion protein is a recombinant hirudin fusion protein incorporating a collagen-binding domain (CBD). The fusion protein of this invention possesses affinity for type I and type III collagen, and can inhibit thrombin activity to exert an anticoagulant effect. Furthermore, it can bind well to collagen-based composite materials, making it suitable for use in cardiovascular implants such as heart valves, cardiac occluders, dialysis membranes, oxygenation membranes, artificial blood vessels, and vascular stents, as well as in extracorporeal circulation and blood purification devices, enhancing anticoagulant and antithrombotic effects.