Occluder based on shape memory composite material and its preparation and application method

Abstract

The invention provides a shape memory composite based plugging device, and a manufacture method and an application method thereof. The manufacture method of the plugging device includes: (1), evenly mixing 90-99 parts of shape memory polymers with 1-5 parts of reinforcing materials and 1-10 parts of magnetic nanoparticles by weight according to an ultrasonic dispersion method to obtain thick liquid, curing the thick liquid, and cutting a cured product into blocky solids; (2), pulling and extruding the blocky solids into filaments, and performing ultraviolet irradiation crosslinking after integral forming via three-dimensional printing to obtain the shape memory composite based plugging device. The shape memory composite based plugging device, and the manufacture method and the application method thereof have the advantages that the plugging device formed through three-dimensional printing is of an integral structure, and the integral structure has high stability and good mechanical property; binding ends are not provided at the ends of the integral structure, and the possibility of thrombus formation on the surface of the device is reduced; a support structure is integrated with a flow choking film, and accordingly, shedding is avoided.

Description

technical field [0001] The invention relates to an occluder, in particular to an occluder based on a shape memory composite material and a preparation and application method thereof. Background technique [0002] Since the first successful application of interventional technology to close atrial septal defect with foramen secundum, interventional therapy has developed rapidly, and various occluders have been proposed successively. [0003] In recent years, some new types of occluders have appeared, such as the occluder invented by Thrill, which uses 22dtex polyester filament knitted fabric as the occluded diaphragm material. Although the reliability of occlusion is increased, the knitted fabric has the ability to resist shedding. Poor diffusion performance, poor self-supporting structure, easy collapse, poor longitudinal and radial compliance, etc.; the occlusive property woven by the memory polymer composite material is introduced into the septal defect area to be occluded ...

AI Technical Summary

Problems solved by technology

[0003] In recent years, some new types of occluders have appeared, such as the occluder invented by Thrill, which uses 22dtex polyester filament knitted fabric as the occluded diaphragm material. Although the reliability of occlusion is increased, the knitted fabric has the ability to resist shedding. Poor diffusion performance, poor self-supporting structure, easy collapse, poor longitudinal and radial compliance, etc.; the occlusive property woven by the memory polymer composite material is introduced into the septal defect area to be occluded by a catheter, The occlusion effect is very significant, but because each shape memory composite material wire has its original shape, the occluder made of weaving is complicated in process, and the weaving will bring the possibility of falling off

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