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Externally applied medicine for treating gout

A medicament and gout technology, applied in the field of external medicaments for the treatment of gout, can solve the problems of colchicine, such as high toxicity, large side effects, and rapid rebound of uric acid, to reduce or relieve pain and discomfort, convenient preparation and application, and combination simple effect

Inactive Publication Date: 2016-10-12
FIRST AFFILIATED HOSPITAL OF KUNMING MEDICAL UNIV +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Western medicine treats the symptoms but not the root cause, and has relatively large side effects; once you stop taking uric acid-lowering drugs during intermittent attacks, uric acid rebounds quickly, and long-term drug control is required; and colchicine is highly toxic and has varying degrees of damage to the human stomach, kidneys, and bone marrow. Harm, do not take advantage of long-term use of patients

Method used

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  • Externally applied medicine for treating gout
  • Externally applied medicine for treating gout
  • Externally applied medicine for treating gout

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] Embodiment 1: the drug efficacy experiment of leaf powder of Moringa oleifera

[0020] The experiment of the rat gouty arthritis model was carried out referring to the method in the existing literature "Improvement of Gouty Arthritis Animal Model", ie the Coderre method. The method is to select healthy SD rats, male, weighing (200±20) g. The rat gout model was prepared by intra-articular injection of MSU suspension 100 mg / mL (prepared in sterile saline), and the joint used in this experiment was the right hind ankle joint of the rat. Ten models were prepared for each of the experimental group and the control group. The control group was not treated, and the experimental group was treated with Moringa leaf powder (made from Moringa leaf powder and distilled water) on the right hind ankle joint. The results were judged 2 hours after the treatment. First, the gait score was performed, and then 1.5 mL of blood was taken from the heart. Finally, the tissues in the ankle joi...

Embodiment 2

[0027] Embodiment 2: the drug effect experiment of Moringa leaf powder and Moringa seed oil mixture

[0028] With the method of Example 1, each of the experimental group and the control group prepared 10 models, wherein the control group did not do any treatment, and the experimental group applied a medicament on the right hind foot and ankle joint. The medicament was composed of Moringa leaf powder and Moringa seed oil. It is modulated at a ratio of 8:2, and the result is judged 2 hours after processing.

[0029] Table 2

[0030]

[0031] Note: * P<0.05.

Embodiment 3

[0032] Embodiment 3: adopt formula: moringa leaf powder 50g, moringa seed oil 10g, safflower powder 10g, barley leaf powder 20g, after raw material is mixed, water is adjusted into paste, and medicament is applied to the limbs of discomfort and swelling and pain caused by gout Joints, 6 times a day (see Table 3);

[0033] Typical case: Patient Li, male, 36 years old, had gout for 3 years, and was admitted to the hospital 2 days after the acute attack of gouty arthritis in the right knee joint. After one day, the pain was obviously relieved, and after one week, the pain was completely eliminated, and the joint function recovered.

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Abstract

The invention discloses an externally applied medicine for treating gout. The externally applied medicine is prepared from moringa leaf powder. The externally applied medicine is applicable to people with uncomfortable and swelling limb joints caused by gout, and has the advantages of nature, no side effect, simple preparation method, low cost, convenience in use, good curative effect, quick response and the like.

Description

technical field [0001] The invention relates to a traditional Chinese medicine, in particular to an external medicine for treating gout. Background technique [0002] With the change of working and living environment, gout, which had a low incidence rate, is increasing day by day and has become a common disease, most of which are men. Gout attacks are common in the thumb joints, toe joints, ankle joints, knee joints and other positions of the feet, with the thumb joints being the most common. Symptoms are severe pain, swelling, erythema, stiffness, warmth, and marked tenderness in the affected joints, and the onset of symptoms is sudden. At present, Western medicine mainly takes colchicine plus analgesic drugs during the onset of the disease to quickly reduce inflammation and relieve the pain; during intermittent onsets, allopurine and other drugs are taken to reduce uric acid and prevent recurrence. Western medicine treats the symptoms but not the root cause, and has rela...

Claims

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Application Information

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IPC IPC(8): A61K36/185A61K36/8998A61P19/06A61P29/00
CPCA61K36/185A61K36/286A61K36/8998A61K2300/00
Inventor 王昆华孙建新徐玉沈宗文任莉张惠锋谢振荣
Owner FIRST AFFILIATED HOSPITAL OF KUNMING MEDICAL UNIV