Application of sharpleaf galangal fruit general flavones in preparation of medicines for treating premenopausal syndrome

Abstract

The invention relates to application of sharpleaf galangal fruit general flavones in preparation of medicines for treating premenopausal syndrome. According to the invention, the application problem of sharpleaf galangal fruit general flavones serving as the unique active ingredient in preparation of medicines for treating premenopausal syndrome can be effectively solved. The sharpleaf galangal fruit general flavones can be prepared by the following steps: grinding sharpleaf galangal fruit into coarse powder, performing reflux extraction by using petroleum ether, degreasing, volatilizing and drying petroleum ether from sharpleaf galangal fruit residues, adding ethanol for soaking, performing reflux extraction, filtering, recovering ethanol under reduced pressure until alcohol flavor is removed, and adding distilled water for dispersing, thereby obtaining the liquid medicine; adding the liquid medicine on AB-8 type macroporous resin, eluting by using distilled water, and removing water elution; eluting by using ethanol with mass concentration of 10%, and removing the elution; and eluting by using ethanol with mass concentration of 80%, recovering ethanol under reduced pressure until alcohol flavor is avoided, performing freeze drying, and grinding, thereby obtaining the sharpleaf galangal fruit general flavones. The sharpleaf galangal fruit general flavone disclosed by the invention is simple in preparation method, easy to operate and high in production efficiency, and is effectively used for preparing medicines for treating premenopausal syndrome.

Description

technical field [0001] The invention relates to medicine, in particular to the application of total flavonoids of Yizhiren in the preparation of medicines for treating premenopausal syndrome. Background technique [0002] Yizhiren is the fruit of Alpinia oxyphylla Miq., a plant of the ginger family. It has the effects of warming the spleen, stopping diarrhea, catching saliva, warming the kidney, reducing urination and consolidating essence. It is often used for spleen and stomach deficiency, vomiting, diarrhea, cold pain in the abdomen, Excessive salivation, kidney deficiency enuresis, frequent urination, nocturnal emission, white turbidity. [0003] Premenopausal syndrome refers to a series of physical and mental symptoms caused by the fluctuation or decrease of sex hormones in women before menopause. Menopause is divided into natural menopause and artificial menopause. Natural menopause refers to menopause caused by physiological depletion of ovarian follicles; artificia...

AI Technical Summary

Problems solved by technology

[0004] Although there are a variety of drugs for the treatment of premenopausal syndrome, there is no application of the total flavonoids of Yizhiren extracted from Yizhiren in the preparation of drugs for the treatment of premenopausal syndrome.

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