Powder aerosol moving type oro-nasal inhalation and contamination device

Abstract

The invention relates to a powder aerosol moving type oro-nasal inhalation and contamination device which comprises an exposure chamber, an experimental animal fixator, an air compressor, a powder diffuser, a diffusion airflow pipe, a vibration device, a powder aerosol sample injection pipe, a hedging type blending chamber, a hedging dilution airflow pipe, a fan and a microprocessor control unit. The powder diffuser is used for solving the problem of quantitative spraying and diffusion of solid test substance powder; the powder diffuser is connected with the hedging type blending chamber through the powder aerosol sample injection pipe, the hedging type blending chamber is fixed to the top of the exposure chamber and communicated with the inside of the exposure chamber, the exposure chamber is provided with an exposure chamber port, the front end of the experimental animal fixator is connected with the exposure chamber through the exposure chamber port, and the microprocessor control unit is used for regulating operating parameters of the contamination device. The powder aerosol moving type oro-nasal inhalation and contamination device simulates a powder aerosol exposure mode in an actual environment, the concentration of test substances is distributed evenly, an exposure state is stable, experimental result repeatability is good, and the powder aerosol moving type oro-nasal inhalation and contamination device is fast and convenient to operate and wide in applied range.

Description

technical field [0001] The invention relates to an experimental device, in particular to a powder aerosol dynamic inhalation poisoning device through mouth and nose. Background technique [0002] Existing powder aerosol inhalation exposure exposure equipment mainly includes static inhalation exposure exposure and dynamic inhalation exposure exposure exposure equipment. The disadvantages of the static inhalation exposure exposure cabinet are: the concentration of the test substance in the exposure cabinet gradually decreases (for the powder aerosol, due to the sedimentation, the concentration will obviously decrease); the experimental animals may be absorbed through the skin; As the experiment progressed, the partial pressure of oxygen decreased significantly. The disadvantages of the existing dynamic inhalation poisoning equipment are: the test substance flows in the form of powder aerosol at high speed in a pipe with a small inner diameter, which does not conform to the ex...

AI Technical Summary

Problems solved by technology

The disadvantages of the static inhalation exposure exposure cabinet are: the concentration of the test substance in the exposure cabinet gradually decreases (for the powder aerosol, due to the sedimentation, the concentration will obviously decrease); the experimental animals may be absorbed through the skin; During the experiment, the partial pressure of oxygen decreased significantly

The disadvantages of the existing dynamic inhalation poisoning equipment are: the test substance flows in the form of powder aerosol at high speed in a pipe with a small inner diameter, which does not conform to the exposure method of the actual environment, and consumes a large amount of the test substance at the same time; For powders with poor fluidity (easy to accumulate and agglomerate), quantitative control cannot be accurately achieved, and may cause pipeline blockage; the structure and control are more complicated and difficult to operate

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