Water-based heat-sealing adhesive for pharmaceutical blisters and preparation method thereof

Abstract

The invention provides an aqueous thermal-sealing adhesive for a medicine bubble cap and a preparation method of the aqueous thermal-sealing adhesive. The aqueous thermal-sealing adhesive comprises the following components: a polyester emulsion, a modified polyolefin emulsion, a polyurethane emulsion, an additive, a tackifier, glycol, glycerol, ethanol and water. The preparation method of the aqueous thermal-sealing adhesive comprises the following steps: uniformly mixing the polyester emulsion, the polyurethane emulsion and the modified polyolefin emulsion, and adding the mixture of the ethanol, the water, the glycol and propylene glycol; adding the additive and the tackifier, stirring, and aging; detecting the solid content of a product, adjusting the solid content to be a theoretic value, stirring, and discharging a material. The aqueous thermal-sealing adhesive has the beneficial effects that as halogen-free environment-friendly aqueous adhesive, the aqueous thermal-sealing adhesive is very good in thermal sealing strength on PTP, PVC, thermal strip aluminum and PVC, and is free of an oily color change problem, excellent in thermal resistance and freeze-thaw stability, good in leveling property and free of corrosion to cutters of a coating machine, and the uniformity of dry measure of the coating process can be ensured.

Description

technical field [0001] The invention relates to a water-based heat-sealing glue used for medicine blisters and a preparation method thereof, belonging to the technical field of heat-sensitive adhesives. Background technique [0002] The aluminum-plastic blister packaging of pharmaceuticals is divided into PTP aluminum foil packaging and tropical aluminum blister packaging, both of which are bonded between aluminum foil and PVC. PTP packaging is to put the plastic sheet on the electric heater to soften it first, then place the sheet in the abrasive tool, and then fill the sheet with compressed air from the upper mold or vacuum the lower mold to make the sheet form a blister or cavity. , cooled after molding, put the medicine in the blister, and the side of the medicinal aluminum foil coated with the adhesive is heat-sealed with the plastic sheet containing the medicine under certain temperature, pressure and time conditions to form a blister packaging PTP packaging material ...

AI Technical Summary

Problems solved by technology

[0005] 2. Because acidity will cause corrosion to the screen roll and equipment on the coating machine during the production process of pharmaceutical packaging, the screen roll will turn black, and the coating amount will be uneven and the equipment will rust;

[0006] 3. The heat sealing strength of the glue will decrease over time;

[0008] 5. The freeze-thaw stability of the polyester and chlorinated vinegar type glue is poor and easy to gel, which affects the use;

[0009] 6. Due to the rapid packaging of medicines in the medicine packaging factory, due to the decomposition of part of the glue, a pungent smell is produced, which seriously affects the progress of production;

[0010] It is precisely because of the above-mentioned disadvantages of traditional VC that greatly limit the development of the pharmaceutical packaging industry

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