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Synergistic tiamulin fumarate premixing agent and preparation method thereof

A technology of tiamulin fumarate and premix, which is applied in the field of synergistic tiamulin fumarate premix and its preparation, can solve the problems of affecting the growth of livestock and poultry, increasing the cost of treatment, and the emergence of drug-resistant bacteria. Improve breathing difficulties, enhance antibacterial efficacy, and improve ventilation function

Inactive Publication Date: 2017-03-15
四川伴农动保生物技术有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Single use of antibiotics without treating both symptoms and root causes, and the treatment time is very long
Prolonged use of antibiotics will not only increase the cost of treatment, affect the growth of livestock and poultry, increase the ratio of feed to meat, but also discharge a large amount of antibiotics to nature through animals, pollute the environment, and cause a large number of drug-resistant bacteria to emerge

Method used

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  • Synergistic tiamulin fumarate premixing agent and preparation method thereof
  • Synergistic tiamulin fumarate premixing agent and preparation method thereof
  • Synergistic tiamulin fumarate premixing agent and preparation method thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0017] A synergistic tiamulin fumarate premix is ​​prepared from the following raw materials in percentage by weight: 80% tiamulin fumarate, 0.5% alpha-asarone, 10% starch and 9.5% corncob powder.

[0018] A preparation method of a synergistic tiamulin fumarate premix: first weigh the tiamulin fumarate, α-asarone, and corncob powder according to weight percentage, grind them through a 120-mesh sieve respectively, and grind the starch through a 120-mesh sieve. The starch slurry with a concentration of 10% is made by the slurry method, and then the tiamulin fumarate, α-asarone and corn cob powder are mixed evenly, and the starch slurry is added to make a soft material, which is granulated with a 18-mesh nylon sieve and baked. After drying, pass through a 12-mesh sieve for granulation.

Embodiment 2

[0020] A synergistic tiamulin fumarate premix is ​​prepared by mixing the following raw materials in percentage by weight: 10% tiamulin fumarate, 4% alpha-asarone, 2% starch and 84% corncob powder.

[0021] A preparation method of a synergistic tiamulin fumarate premix: first weigh the tiamulin fumarate, α-asarone, and corncob powder according to weight percentage, grind them through a 120-mesh sieve respectively, and grind the starch through a 120-mesh sieve. The starch slurry with a concentration of 10% is made by the slurry method, and then the tiamulin fumarate, α-asarone and corncob powder are mixed evenly, and the starch slurry is added to make a soft material, which is granulated with a 18-mesh nylon sieve and baked. After drying, pass through a 12-mesh sieve for granulation.

Embodiment 3

[0023] A synergistic tiamulin fumarate premix is ​​prepared from the following raw materials in percentage by weight: 45% tiamulin fumarate, 3% alpha-asarone, 6% starch and 46% corncob powder.

[0024] A preparation method of a synergistic tiamulin fumarate premix: first weigh the tiamulin fumarate, α-asarone, and corncob powder according to weight percentage, grind them through a 120-mesh sieve respectively, and grind the starch through a 120-mesh sieve. The starch slurry with a concentration of 10% is made by the slurry method, and then the tiamulin fumarate, α-asarone and corn cob powder are mixed evenly, and the starch slurry is added to make a soft material, which is granulated with a 18-mesh nylon sieve and baked. After drying, pass through a 12-mesh sieve for granulation.

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Abstract

The invention discloses a synergistic tiamulin fumarate premixing agent, which is prepared from the following raw materials including tiamulin fumarate, alpha-asarin, starch and corncob powder through mixing, pelleting and drying. A preparation method of the synergistic tiamulin fumarate premixing agent comprises the following steps that firstly, the tiamulin fumarate, the alpha-asarin and the corncob powder are weighed, and are respectively ground and sieved by a sieve; the starch is prepared into starch slurry by a slurry flushing method; then, the tiamulin fumarate, the alpha-asarin and the corncob powder are uniformly mixed; then, the starch slurry is added to prepare a soft material; pelleting and drying are performed; after the drying, the material is sieved by a sieve screen; particle sorting is performed. The synergistic tiamulin fumarate premixing agent and the preparation method of the premixing agent have the advantages that the tiamulin fumarate and the alpha-asarin are skillfully combined; found by long-period experiments, the alpha-asarin can improve a ventilation function and relieve the difficult breathing condition; the distribution concentration of the tiamulin in the lung can also be increased; the antibacterial curative effect is enhanced; the disease course is shortened; the antibiotic consumption is reduced.

Description

technical field [0001] The invention belongs to the technical field of animal medicines, and in particular relates to a synergistic tiamulin fumarate premix and a preparation method thereof. Background technique [0002] In the current large-scale breeding process, mycoplasma pneumonia is a very headache and difficult to solve disease. The course of the disease is long and easy to recur. The usual treatment method is to use antibiotic preparations such as tylosin tartrate, doxycycline hydrochloride, florfenicol, etc. for mixing or drinking water. The single use of antibiotics does not treat both symptoms and root causes, and the treatment time is very long. Prolonged use of antibiotics will not only increase treatment costs, affect the growth of livestock and poultry, increase the feed-to-meat ratio, but also excrete a large amount of antibiotics to nature through animals, pollute the environment, and cause a large number of drug-resistant bacteria to emerge. Contents of...

Claims

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Application Information

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IPC IPC(8): A61K9/16A61K31/22A61K31/09A61K47/36A61K47/46A61P31/04A61P11/00
CPCA61K31/22A61K9/1652A61K9/1664A61K31/09A61K2300/00
Inventor 郭金鹏周可刚
Owner 四川伴农动保生物技术有限公司
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