Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Konjac and red yeast rice compound lipid-lowering capsule and preparation method thereof

A blood lipid-lowering capsule technology, which is applied in the field of blood-lipid-lowering products, can solve problems such as unsatisfactory effects, liver damage, temporary fixes, etc., to inhibit the formation of atherosclerotic plaques, protect vascular endothelial cells, and inhibit liver damage. deposition effect

Inactive Publication Date: 2017-06-13
山东省内分泌与代谢病研究所
View PDF2 Cites 3 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Currently commonly used blood lipid-lowering drugs are metabolized by the liver, which has side effects of liver damage and myolysis, and once the drug is stopped, blood lipid rebound will occur, and the effect is not very satisfactory.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Konjac and red yeast rice compound lipid-lowering capsule and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0038] The preparation method of konjac red yeast rice compound hypolipidemic capsule comprises the following steps:

[0039] (1) Raw material pretreatment:

[0040] Get 350 parts of konjac fine powder, 150 parts of red yeast rice powder; Konjac fine powder and red yeast rice powder are all crossed 80 mesh sieves;

[0041] The preparation method of konjac powder is as follows:

[0042]a Take fresh washed fresh konjac, peel it, cut it into pieces, then mix it with ethanol solution and put it into the pulverizer together for pulverization, and add effective SO at the same time 2 A sulfite solution with a concentration of 25mg / L to 100mg / L; the ethanol solution is 1-3 times the weight of fresh konjac, and the concentration of ethanol in the material is greater than or equal to 30%; the crushed material is sent to a grinding wheel mill for further crush;

[0043] b Put the material pulverized by the grinding wheel in step a into a centrifuge with a filter screen, the soluble ma...

Embodiment 2

[0078] The preparation method of konjac red yeast rice compound hypolipidemic capsule comprises the following steps:

[0079] (1) Raw material pretreatment:

[0080] Get 300 parts of konjac fine powder, 100 parts of red yeast rice powder; Konjac fine powder and red yeast rice powder are all crossed 80 mesh sieves;

[0081] (2) mixing:

[0082] The konjac fine powder and red yeast rice powder in step (1) were mixed, and the mixing time was 20 minutes; the preparation method of konjac fine powder was the same as Example 1;

[0083] (3) Preparation of capsules

[0084] Get the mixed raw materials in step (2), send them into the capsule filling chamber for capsule filling, the capsule filling chamber and the outer chamber maintain a relative negative pressure, the dust is removed by the dust collection device, the indoor control temperature is 18°C, and the relative humidity is 45%, and the compound recipe is obtained. Konjac hypolipidemic capsules. Disintegration time limit o...

Embodiment 3

[0086] The preparation method of konjac red yeast rice compound hypolipidemic capsule comprises the following steps:

[0087] (1) Raw material pretreatment:

[0088] Get 400 parts of konjac fine powder, 200 parts of red yeast rice powder; Konjac fine powder and red yeast rice powder are all crossed 80 mesh sieves;

[0089] (2) mixing:

[0090] Konjac fine powder and red yeast rice powder in step (1) were mixed, and the mixing time was 40 minutes;

[0091] (3) Preparation of capsules

[0092] Get the mixed raw materials in step (2), send them into the capsule filling chamber for capsule filling, the capsule filling chamber and the outer chamber maintain a relative negative pressure, the dust is removed by the dust collection device, the indoor control temperature is 26°C, and the relative humidity is 65%, and the compound recipe is obtained. Konjac hypolipidemic capsules. Disintegration time limit of filled capsules: 30min.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
Viscosityaaaaaaaaaa
Login to View More

Abstract

The invention belongs to the field of lipid-lowering products, particularly relates to a konjac and red yeast rice compound lipid-lowering capsule and also relates to a preparation method of the capsule. The compound lipid-lowering capsule is characterized by being prepared from the following components in parts by weight: 300-400 parts of konjac refined flour and 100-200 parts of red yeast rice powder. The compound lipid-lowering capsule has the beneficial effects that the konjac refined flour is combined with the red yeast rice powder for synergistic action, so that the compound lipid-lowering capsule has the functions of regulating blood fat, reducing serum cholesterol, triglyceride, low-density lipoprotein cholesterin and increased high-density lipoprotein cholesterol, inhibiting formation of atherosclerotic plaques, protecting vascular endothelial cells and inhibiting lipid deposition in the liver.

Description

technical field [0001] The invention belongs to the field of blood fat-lowering products, in particular to konjac red yeast rice compound blood fat-lowering capsules, and also relates to a preparation method of the capsules. Background technique [0002] According to the "Report on Nutrition and Chronic Diseases of Chinese Residents (2015)" released by the Health and Family Planning Commission, in 2012, the prevalence of hypertension in adults aged 18 and above was 25.2%, and the prevalence of diabetes was 9.7%, compared with 2002 , the prevalence is on the rise. According to the "Second China Urban Health Survey" released by the Chinese Medical Doctor Association in 2011, nearly half of the young and middle-aged people in my country have dyslipidemia. A report from the US Centers for Disease Control and Prevention shows that among adults over the age of 20, at least 45% suffer from one of hyperlipidemia, high blood pressure, and diabetes, and 9% suffer from high blood pres...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K36/888A61K36/899A61K9/48A61P3/06
CPCA61K36/888A61K9/48A61K36/062A61K36/899A61K2236/19A61K2236/333A61K2236/51A61K2300/00
Inventor 丁文宇张宪党王志斌丁丽娜
Owner 山东省内分泌与代谢病研究所
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com