Fast high-selectivity super-sensitive nickel ion colorimetric fluorescent probe and preparation method thereof
A nickel ion, fluorophore technology, applied in fluorescence/phosphorescence, chemical instruments and methods, luminescent materials, etc., can solve the problems of complex synthesis, insufficient sensitivity, and insufficient response speed, and achieve simple synthesis, good stability, Responsive effect
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[0032] Example 1
[0033]
[0034] (Scheme 1) Dissolve 410.5mg (1mmol) of rhodamine-like fluorophore compound in 15mL of anhydrous dichloromethane, then add 120.5mg (1mmol) of allyl chloroformate, then stir and react at 25°C for 3h. After the reaction is complete Rotate to dry the dichloromethane to obtain the crude product. Finally, a mixed system of dichloromethane and petroleum ether (1:5, v / v) was used for column chromatography to obtain 306.6 mg of pure pink product with a yield of 62%.
[0035] (Scheme 2) Dissolve 410.5mg (1mmol) of rhodamine-like fluorophore compound in 15mL of anhydrous dichloromethane, then add 180.8mg (1.5mmol) of allyl chloroformate, then stir and react at 25°C for 3h, the reaction is complete Then, the methylene chloride was evaporated to dryness, and the crude product was obtained. Finally, a mixed system of dichloromethane and petroleum ether (1:5, v / v) was used for column chromatography to obtain 385.7 mg of pure pink product with a yield of 78%.
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[0039] Example 2
[0040] Figure 1(a) is a graph showing the change of the fluorescence spectrum of a nickel ion colorimetric fluorescent probe (20μM) after adding nickel ions (0-5μM). It can be clearly seen from the figure that as the concentration of nickel ions increases, the fluorescence intensity at 645 nm of the solution gradually increases. Moreover, it can be seen from the inset that the fluorescence intensity at 645 nm has a good linear relationship with the concentration of nickel ions added, which proves that the fluorescent probe can be used to quantitatively analyze nickel ions.
[0041] Figure 1(b) is a graph showing the change in the absorption spectrum of a nickel ion colorimetric fluorescent probe (20μM) after adding nickel ions (0-2μM). It can be seen from the figure that as the concentration of nickel ions increases, the absorbance value of the solution at 580nm gradually increases. From the illustration, we can clearly see that after nickel ions are added, the...
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[0042] Example 3
[0043] figure 2 It is a graph of the change of the fluorescence spectrum of nickel ion colorimetric fluorescent probe (20μM) with nickel ion (2μM) over time. It can be clearly seen from the figure that when nickel ions are added, the fluorescence intensity reaches the maximum value and remains unchanged after 2 minutes, which shows that the probe reacts quickly with nickel ions and can provide a fast analytical method for the determination of nickel ions.
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