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Pharmaceutical composition for treating acute soft-tissue injury

A soft tissue injury and composition technology, applied in the field of pharmaceutical compositions for the treatment of acute soft tissue injury, can solve the problems such as the pharmaceutical compositions of berberine and geniposide that are not disclosed, and achieve widening the scope of disease prevention and treatment and relieving pain symptoms , the effect of treatment of soft tissue injury

Inactive Publication Date: 2017-06-30
FOSHAN HOSPITAL OF TCM
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

After searching, there is no patent document disclosing the pharmaceutical composition of berberine and geniposide for the treatment of acute soft tissue injury, nor is there a pharmaceutical composition of berberine and geniposide listed as a drug for the treatment of acute soft tissue injury.

Method used

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  • Pharmaceutical composition for treating acute soft-tissue injury
  • Pharmaceutical composition for treating acute soft-tissue injury
  • Pharmaceutical composition for treating acute soft-tissue injury

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] The preparation of embodiment 1-lotion

[0024] Recipe: berberine hydrochloride (active ingredient) 5kg, geniposide (active ingredient) 5kg, ethylparaben (preservative) 1kg, sodium benzoate (preservative) 2kg, appropriate amount of distilled water (solvent).

[0025] Preparation method: Dissolve the active ingredient and other auxiliary materials in distilled water, set the volume to 1000L, subpackage, and sterilize to obtain the product.

[0026] How to use: Dip gauze or cotton swab into the liquid medicine, wash or wet compress the affected area, twice a day.

Embodiment 2

[0027] The preparation of embodiment 2-lotion

[0028] Formula: berberine hydrochloride (active ingredient) 100kg, geniposide (active ingredient) 5kg, ethylparaben (preservative) 1kg, sodium benzoate (preservative) 2kg, appropriate amount of distilled water (solvent).

[0029] Preparation method: Dissolve the active ingredient and other auxiliary materials in distilled water, set the volume to 1000L, subpackage, and sterilize to obtain the product.

[0030] How to use: Dip gauze or cotton swab into the liquid medicine, wash or wet compress the affected area, twice a day.

Embodiment 3

[0031] The preparation of embodiment 3-lotion

[0032] Recipe: 250kg of berberine hydrochloride (active ingredient), 5kg of geniposide (active ingredient), 1kg of ethylparaben (preservative), 2kg of sodium benzoate (preservative), appropriate amount of distilled water (solvent).

[0033] Preparation method: Dissolve the active ingredient and other auxiliary materials in distilled water, set the volume to 1000L, subpackage, and sterilize to obtain the product.

[0034] How to use: Dip gauze or cotton swab into the liquid medicine, wash or wet compress the affected area, twice a day.

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Abstract

The invention relates to the technical field of natural medicine, particularly relates to a pharmaceutical composition for treating acute soft-tissue injury. Compared with the existing routine medication, the pharmaceutical composition has better therapeutic effect and overcomes the shortcomings of the existing drugs for treating acute soft-tissue injury used in clinic, especially for the defects of long treatment course and slow healing, and provides a pharmaceutical composition with rapid effect initiating, low cost and small side effect. The weight ratio of berberine to geniposide is (1-100):1. The pharmaceutical composition is an external preparation such as a lotion, a spray, an ointment and a gel. The invention provides the pharmaceutical composition composed of the traditional Chinese medicine monomer components for the treatment of acute soft-tissue injury, which has the advantages of clear function and non-toxic and side effect, and widens the range of preventing and curing diseases by the berberine and the geniposide.

Description

technical field [0001] The invention relates to the technical field of natural medicines, in particular to a pharmaceutical composition for treating acute soft tissue injury. Background technique [0002] Berberine is an isoquinoline alkaloid with a molecular formula of C20H18NO4 and a molecular weight of 235.32. It exists in many plants of 4 families and 10 genera including Berberidaceae. Studies have shown that berberine has a wide antibacterial spectrum and has antibacterial effects on a variety of Gram-positive and negative bacteria in vitro, including hemolytic streptococcus, Staphylococcus aureus, Vibrio cholerae, meningococcus, Shigella dysenteriae, Typhoid bacillus, diphtheria bacillus, etc. have a strong inhibitory effect, inhibiting bacteria at low concentrations, and sterilizing at high concentrations. It also has a certain inhibitory effect on influenza virus, amoeba, leptospira, and some skin fungi. Berberine hydrochloride (commonly known as berberine hydrochl...

Claims

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Application Information

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IPC IPC(8): A61K31/4375A61K31/7048A61P19/04A61P29/00
CPCA61K31/4375A61K31/7048A61K2300/00
Inventor 刘效仿余俊文李子鸿李怀国刘东文郑芳昊刘礼初李雪蔡立雄
Owner FOSHAN HOSPITAL OF TCM
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