Platinum-copper nanocrystals as tumor photothermal ablation diagnosis and treatment agent and preparation method thereof

A technology of photothermal ablation and platinum copper, which is applied in the direction of antineoplastic drugs, medical preparations containing active ingredients, pharmaceutical formulas, etc., to achieve the effects of good crystal form, reduced dosage, and good structural stability
CN106913871AActive Publication Date: 2017-07-04HENAN UNIV OF SCI & TECH
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Patent Information

Authority / Receiving Office
CN ¡ China
Current Assignee / Owner
HENAN UNIV OF SCI & TECH
Publication Date
2017-07-04

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Abstract

The invention relates to platinum-copper nanocrystals as a tumor photothermal ablation diagnosis and treatment agent and a preparation method thereof, and belongs to the technical field of nano biomaterials. The platinum-copper bimetallic nanocrystals have the particle size in a range of 5-200 nm and have the basic structure of PtCun, wherein n is in the range of 0-5; the morphology has one or more of cube, sphere, snowflake shape, and lamellar shape. The platinum-copper nanocrystals can be applied to near infrared light mediated tumor photothermal ablation, and are applicable to the near infrared light wavelength range of 700-1100 nm. The platinum-copper nanocrystals are prepared by a pyrolysis method, and in a high-boiling-point oil phase medium, the snowflake-shaped platinum-copper bimetallic nanocrystals are prepared by metal precursor thermal reduction decomposition. The nanocrystals have the advantages of low cost, simple preparation, high purity, good crystal shape, controllable particle size and regular shape, are used as a near infrared photothermal conversion agent to be applied to tumor photothermal ablation, have obvious effect, and provide a research direction for tumor therapy.
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Description

technical field

[0001] The invention belongs to the technical field of nano-biological materials, and in particular relates to a platinum-copper nanocrystal used as a photothermal ablation diagnosis and treatment agent for tumors and a preparation method thereof. Background technique

[0002] With the development of nanotechnology, noble metal nanomaterials have outstanding catalytic, electromagnetic and optical properties due to the effective superposition of their inherent surface effects, quantum size effects and interface effects, making them the richest materials in the field of nanotechnology. It is a dynamic sub-discipline and plays an important role in the development of modern industry, national defense and high technology.

[0003] In recent years, platinum-based nanomaterials have been widely used in many fields due to their excellent photothermal conversion, hydrogenation catalysis and electrical sensing properties. However, as a rare precious metal, its limited...

Claims

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