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A Concentration Sensor Based on Fiber Optic Manipulation of Single Microspheres

A technology of concentration sensor and monodisperse microspheres, which is applied in the field of sensors, can solve the problems of high cost and complicated processing process, and achieve the effects of high sensitivity, simple processing process and low preparation cost

Active Publication Date: 2019-11-05
UNIV OF ELECTRONICS SCI & TECH OF CHINA
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Problems solved by technology

But both require more complex processing, resulting in higher costs

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  • A Concentration Sensor Based on Fiber Optic Manipulation of Single Microspheres
  • A Concentration Sensor Based on Fiber Optic Manipulation of Single Microspheres
  • A Concentration Sensor Based on Fiber Optic Manipulation of Single Microspheres

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Embodiment Construction

[0016] The present invention will be further described in detail below in conjunction with the embodiments and the accompanying drawings.

[0017] This embodiment provides a concentration sensor based on an optical fiber to control a single microsphere, its structure is as follows figure 1 As shown, this embodiment takes the measurement of the concentration of sodium chloride solution as an example, wherein polystyrene microspheres are used as monodisperse microspheres; the computer is used in conjunction with the microscope 4 with CCD for real-time detection of the control distance. The specific project of its work includes the following steps:

[0018] Step 1: Turn on the computer, turn on the microscope, open the supporting software of the microscope on the computer, place the microfluidic chip on the stage of the microscope, adjust its position, set the exposure time, contrast, etc., to achieve the best observation effect;

[0019] Step 2: Add polystyrene microspheres to...

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Abstract

The invention belongs to the technical field of sensors, and provides a concentration sensor based on optical fiber to control a single microsphere, including a microfluidic chip, a monodisperse microsphere, a micro-sampling pump, a micro-sampler, a single-mode optical fiber, a pump laser, and a sensor with a CCD. The microscope is characterized in that: a microfluidic channel is integrated in the microfluidic chip, one end of the single-mode optical fiber is a flat end face, the flat end face is placed in the microfluidic channel and is coaxial with the microfluidic channel, and the other end of the single-mode optical fiber is connected to the pump Laser; the monodisperse microspheres are added to the solution to be tested, the micro sampler extracts the solution to be tested, and injected into the microfluidic channel through a micro-injection pump; the pump laser generates a pump laser that is transmitted through a single-mode optical fiber and passed through a flat end face In the exit, the microscope with CCD is used to detect the distance between the microsphere and the flat end surface of the optical fiber in real time, and the concentration sensing is realized through the distance detection. The concentration sensor of the invention has high sensitivity, simple processing process, low preparation cost and easy integration with microfluidic chips.

Description

technical field [0001] The invention belongs to the technical field of sensors, in particular to a concentration sensor for manipulating a single microsphere based on an optical fiber. Background technique [0002] Traditional optical fiber concentration sensing is based on micro-interferometers or grating structures; interferometric concentration sensors are based on phase demodulation and have high sensitivity; grating concentration sensors are based on wavelength demodulation and have multiplexing potential. But both require more complex processing, resulting in higher costs. The invention proposes a concentration sensor based on optical fiber to control a single microsphere. The processing method is simple, and it can be obtained by cutting a single-mode optical fiber; the optical fiber control is based on the optical force effect. Sensitive potential; the sensor can sense the change of weak Stokes resistance caused by the change of solution concentration, which is a no...

Claims

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Application Information

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IPC IPC(8): G01N15/14
CPCG01N15/1434
Inventor 龚元邹文亮张晨琳饶云江
Owner UNIV OF ELECTRONICS SCI & TECH OF CHINA
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