Mini-type wearable non-invasive blood glucose monitor
A blood glucose monitor and wearable technology, applied in the field of miniature wearable non-invasive blood glucose monitor, can solve the problem that the shape, specification or operation and use are not suitable for human body detection, measurement result accuracy, stability and repeatability Unsatisfactory performance, inability to meet live detection, dynamic real-time monitoring and rapid detection, etc., to achieve the effect of easy fixation and testing, good man-machine combination effect, and wide application range
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Embodiment 1
[0048] A miniature wearable non-invasive blood glucose monitor, such as figure 1 As shown, it includes a fiber optic probe, a laser 1, and a spectral detector 6;
[0049] The optical fiber probe includes a laser channel, a Raman scattering collection channel and a detection channel;
[0050] An incident optical fiber (3), a first collimator lens 4, and a first optical filter 10 are sequentially arranged in the laser channel along the propagating direction of the incident laser light;
[0051] The incident optical fiber 3 transmits the incident laser light to the first collimating lens 4, and the direction of the incident laser light is controlled by the first collimating lens 4, so that the incident laser light is accurately directed to the first optical filter 10, and the first optical filter 10 Only lasers with specific wavelengths are allowed to pass through;
[0052] The detection channel is respectively connected to the laser channel and the Raman scattering channel thr...
Embodiment 2
[0065] On the basis of Example 1, this embodiment provides the method for calculating blood glucose concentration by partial least squares method, including:
[0066] The blood glucose concentration Y is obtained by formula (1):
[0067] Y=f(x)+Error (1)
[0068] In formula (1), f(x) is the dominant factor:
[0069] f(x)=k 1 x 1 +k 2 x 2 +…+k n x n +k n+1 x 1 2 +k n+2 x 2 2 +…+k 2n x n 2 +b
[0070] Among them, n is the number of characteristic peaks in the spectrum with the same position as the glucose standard spectrum, x n is the area of the characteristic peak at the same position as the standard spectrum of glucose in the spectrum, k 1 ,k 2 ,...,k 2n is the first coefficient;
[0071] In this embodiment, the partial least squares method is used to obtain k 1 ,k 2 ,...,k 2n ;
[0072] Error means residual, Error=j 1 x' 1 +j 2 x' 2 +…+j m x' m +j m+1 x' 2 1 +j m+2 x' 2 2 +…+j 2m x' 2 m +c
[0073] Among them, m is the number of rem...
Embodiment 3
[0077] On the basis of Embodiment 1, this embodiment further includes a wristband 15 on which the self-focusing lens 13 is arranged.
[0078] The probe provided in Embodiment 1 can be fixed on a living body, especially a human body (such as a human wrist, arm, etc.) through a wrist strap and Velcro, not only capable of single detection, but also dynamic real-time monitoring.
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