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Whitening composition comprising scutellaria alpina extract

A technology of scutellaria baicalensis extract and composition, applied in the field of compositions containing alpine baicalensis baicalensis extract, can solve problems such as unsatisfactory skin whitening effect, low efficacy, skin allergies, etc., and achieve the effect of reducing melanin production

Inactive Publication Date: 2017-09-26
AMOREPACIFIC CORP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, its utility is not that high due to suboptimal skin whitening effect, low stability, and skin irritation

Method used

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  • Whitening composition comprising scutellaria alpina extract
  • Whitening composition comprising scutellaria alpina extract
  • Whitening composition comprising scutellaria alpina extract

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0090] [Example 1] Preparation of Alpine Scutellaria alpina (Scutellaria alpina) Extract

[0091] The flowers, leaves and stems of Scutellaria baicalensis are harvested, dried with hot air and crushed into powder. The resulting powder was extracted with ethanol / water solution, and then ethanol was removed by vacuum distillation. After adding glycerin and a preservative to the resulting concentrate, Scutellaria baicalensis was obtained by filtration. From DSM Nutritional Products Ltd. (4002Basel, Switzerland) purchase the Scutellaria baicalensis extract ( SCUTELLARIA AO) for the following test examples.

Embodiment 2

[0115] [Dosage Form Example 2] Tablet

[0116] 8 mg of the Scutellaria baicalensis extract of Example 1, 9 mg of vitamin E, 9 mg of vitamin C, 200 mg of galacto-oligosaccharides, 60 mg of lactose and 140 mg of maltose were mixed and a fluidized bed dryer was used. Then, after adding 6 mg of sugar ester, the mixture was prepared into tablets containing 500 mg of the composition according to the usual method.

Embodiment 3

[0117] [Dosage Form Example 3] Drink

[0118] Mix 8 mg of the Scutellaria baicalensis extract of Example 1, 9 mg of vitamin E, 9 mg of vitamin C, 10 g of glucose, 0.6 g of citric acid and 25 g of oligosaccharide syrup, and add 300 mL of purified water. 200 mL of the mixture was filled into bottles. Then, the drink was prepared by sterilizing at 130° C. for 4-5 seconds.

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Abstract

The present specification discloses a composition comprising a Scutellaria alpina extract as an active ingredient. The composition disclosed in the present specification exhibits the effect of reducing melanogenesis or inhibiting tyrosinase activity by comprising the Scutellaria alpina extract. As a result of the effect, the Scutellaria alpina extract of the present specification can exhibit a whitening effect and thus can be widely used as a whitening composition in the field of pharmaceuticals or cosmetics.

Description

technical field [0001] The present invention relates to a composition containing an extract of Scutellaria alpine. Background technique [0002] Melanin is the pigment that determines the color of human skin. Skin color is determined by the amount and distribution of melanin. The cells that produce melanin are derived from melanocytes located in the bottom layer of the epidermis and are lost as a result of skin metabolism moving towards the stratum corneum. Regardless of skin color, the number of melanocytes is almost constant, but the difference in the amount, type and distribution of melanin produced results in different skin colors. [0003] In the skin, the so-called "tyrosinase" converts tyrosine into dopa (dihydroxyalanine) through a series of oxidation processes, and finally turns into brown-black polymer melanin. [0004] Melanin is produced by melanocytes located in the basal layer of the skin. Ultraviolet rays, inflammation, etc. are known to stimulate melanin ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/539A61K36/536A61K8/9789A61P17/00
CPCA61K36/536A61K36/539A61K8/9789A61P17/00A23V2250/21A61K2236/333A61Q19/02A23L2/52A23V2002/00A61K8/0204A61K8/0216A61K8/11A61K2800/782A61K2800/91A61K2800/92A23L33/105
Inventor 朴泌俊李昭希曹恩敬李泰龙
Owner AMOREPACIFIC CORP
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