Brain heart smoothing oral liquid and preparation method thereof

A technology for Naoxinshu oral liquid and culture medium formulation, which is applied to the traditional Chinese medicine preparation Naoxinshu oral liquid for sedation and tranquility and its preparation, in the field of nourishing and strengthening, and can solve the problem that various polypeptide impurities are difficult to remove, the fermentation yield is low, and the Cost increase and other problems, to achieve the effect of significant efficacy, high content and cost saving

Inactive Publication Date: 2017-09-29
颜鑫 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0012] The armillaria concentrate prepared by the prior art has a low fermentation yield and contains a variety of polypeptide impurities that are difficult to remove. If removed, a large amount of resources will be consumed, resulting in increased costs and waste of resources.

Method used

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  • Brain heart smoothing oral liquid and preparation method thereof
  • Brain heart smoothing oral liquid and preparation method thereof
  • Brain heart smoothing oral liquid and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0051] A new fermentation extraction method for Armillaria armillaria, said method comprising the steps of:

[0052] Step 1, primary fermentation

[0053] Medium formula: 200g edible wheat bran, 200g edible soybean meal, 100g starch, 100g sucrose, 100g peptone, 100g fructose syrup, 100ml soybean oil, 40g potassium dihydrogen phosphate, 20g magnesium sulfate, 5g sodium alginate;

[0054] Preparation of culture medium: soak edible wheat bran and edible soybean meal with 5 times the amount of water for 30-60 minutes, heat and boil for 1 hour, filter, cool, add the above-mentioned other raw materials, and stir evenly;

[0055] Cultivation method: add water 37L-39L, sterilize at 0.1-0.2mpa, 121°C for 40 minutes, inoculate Armillaria armillaria in 60L seed tanks by differential pressure method; air is introduced, and the ventilation rate is 1:0.3-1:0.5v / v .min, for 4-6 days, pressure 0.4-0.5×105pa, temperature 26-28°C, pH value 6.20-6.60; obtain Armillaria primary fermentation cultur...

Embodiment 2

[0068] Preparation of Naoxinshu Oral Liquid:

[0069]

[0070] Take 450g of honey and heat it for refining (90-100°C), filter it, let it cool, mix it with the ground royal jelly, then add Armillaria militarum concentrate, 3g of sodium benzoate and ethanol solution of essence, mix well, and adjust the total amount To 1000ml, stir well, filter, that is.

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Abstract

The invention relates to a brain heart smoothing oral liquid and a preparation method thereof. The method comprises the following steps of (1) primary fermentation of armillaria ostoyae; (2) secondary fermentation of the armillaria ostoyae; (3) third-stage fermentation of the armillaria ostoyae; (4) treatment of an armillaria ostoyae fermentation liquid; (5) preparation of the brain heart smoothing oral liquid. The method comprises the steps of heating and refining taken 450g of honey (90-100 DEG C), filtering, cooling and mixing with ground royal jelly evenly; and adding an armillaria ostoyae concentrated solution, 3g of sodium benzoate and an ethanol solution of an essence obtained in the step (4), mixing evenly, adjusting until the total quantity is 1,000ml, stirring evenly and filtering.

Description

Technical field: [0001] The invention relates to a traditional Chinese medicine preparation and a preparation method thereof, in particular to a nourishing and strong Chinese medicine preparation Naoxinshu oral liquid and a preparation method thereof. Background technique: [0002] Naoxinshu Oral Liquid is a Chinese patent medicine preparation that has been marketed to nourish, strengthen, calm and soothe the nerves. It is used for weak body, restlessness, insomnia, dreaminess, neurasthenia, headache and dizziness, which belong to the above syndromes. The formula is as follows: [0003] (1000ml prescription volume) [0004] [0005] Its preparation method is as follows: [0006] Armillaria concentrated solution process: [0007] Put 60% of the volume of the culture medium in the fermenter, heat and sterilize it in water for 30 minutes, connect the third-grade seeds in the seed tank by the pressure difference method, cultivate at 26-28°C for 4-6 days, transfer to the fe...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/07A61K9/08A61K47/12A61P39/00A61P25/20A61P25/00A61P1/08A61P29/00A61K35/644
CPCA61K9/08A61K35/644A61K36/07A61K47/12A61K2300/00
Inventor 颜鑫史红霞
Owner 颜鑫
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