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Medicine for treating meningitis as well as preparation method and application thereof

A technology of meningitis and medicine, applied in the field of medicine, can solve the problems of inability to change the side effects of western medicine, difficulties for medical staff, long course of conjunctivitis, etc., and achieve the effect of no toxic side effects, significant curative effect, and simple preparation process

Inactive Publication Date: 2017-09-29
佳木斯大学附属第一医院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Due to the long course of tuberculosis, it brings great financial and spiritual burdens to patients and their families, and brings many difficulties to medical staff
The existing treatment method is to use western medicine, which has a long course of treatment and severe side effects. Some also use western medicine as the main method and traditional Chinese medicine as an auxiliary method, but the side effects of western medicine still cannot be changed.

Method used

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  • Medicine for treating meningitis as well as preparation method and application thereof
  • Medicine for treating meningitis as well as preparation method and application thereof
  • Medicine for treating meningitis as well as preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] In the embodiment of the present invention, a medicine for the treatment of meningitis is composed of the following raw materials: 18 kg of Tinglizi, 1 kg of deer horn tablets, 21 kg of corn silk, and 9 kg of melon.

[0029] The Tinglizi and Gualou were crushed and passed through a 60-mesh sieve, then soaked in a 60% ethanol aqueous solution at room temperature for 1.2 hours, and then microwaved twice at a temperature of 55°C and a microwave power of 800W, each time 6min, a mixed solution A was prepared. The corn silk was crushed, passed through a 100-mesh sieve, and 15 times its mass was added to deionized water for ultrasonic extraction. The ultrasonic temperature was 75°C, the ultrasonic frequency was 900W, and the ultrasonic treatment time was 1.2h. After ultrasonic, the supernatant was centrifuged to obtain the supernatant; The speed is 10000r / min, and the centrifugal time is 5min. Crush the deer horn flakes, pass through a 200 mesh sieve, add 6.2 times the mass of d...

Embodiment 2

[0031] In the embodiment of the present invention, a medicine for the treatment of meningitis is composed of the following raw materials: Tinglizi 26kg, deer horn tablets 5kg, corn silk 29kg, and Trichosanthes 17kg.

[0032] The Tinglizi and Gualou are crushed and passed through an 80-mesh sieve, then soaked in a 60% ethanol aqueous solution at room temperature for 1.5 hours, and then microwaved twice at a temperature of 58°C and a microwave power of 800W, each time 10min, a mixed solution A was prepared. The corn silk was crushed and passed through a 120-mesh sieve, and 17 times the mass of deionized water was added for ultrasonic extraction. The ultrasonic temperature was 78°C, the ultrasonic frequency was 900W, and the ultrasonic treatment time was 1.5h. After ultrasonic, the supernatant was centrifuged to obtain the supernatant; The speed is 14000r / min, and the centrifugal time is 10min. Crush the deer horn flakes, pass through a 300 mesh sieve, add 6.5 times the mass of dei...

Embodiment 3

[0034] In the embodiment of the present invention, a medicine for treating meningitis is composed of the following raw materials: Tinglizi 20kg, deer horn tablets 2kg, corn silk 23kg, and Trichosanthes 11kg.

[0035] The Tinglizi and Gualou were crushed, passed through a 70-mesh sieve, and then immersed in a 60% ethanol aqueous solution at room temperature for 1.4 hours, and then microwaved twice at a temperature of 56°C and a microwave power of 800W, each time 8min, a mixed solution A was prepared. The corn silk was crushed, passed through a 110-mesh sieve, and 16 times the mass of deionized water was added for ultrasonic extraction. The ultrasonic temperature was 76°C, the ultrasonic frequency was 900W, the ultrasonic treatment time was 1.3h, and the supernatant was centrifuged after ultrasonication; The speed is 12000r / min, and the centrifugal time is 8min. Crush the deer horn flakes, pass through a 250 mesh sieve, add deionized water of 6.4 times its mass, heat to 97°C and s...

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Abstract

The invention discloses a medicine for treating meningitis as well as a preparation method and application thereof. The medicine is composed of the following raw materials in parts by weight: 18-26 parts of semen lepidii, 1-5 parts of sliced cornu cervi, 21-29 parts of corn stigma and 9-17 parts of trichosanthes kirilowii maxim. The preparation method comprises the following steps: grinding semen lepidii and trichosanthes kirilowii maxim, screening, soaking with an aqueous solution of ethanol, performing microwave extraction, and drying so as to obtain the mixed powder; grinding and screening the corn stigma, adding deionized water for performing ultrasonic extraction, and centrifuging to take the supernatant; grinding and screening the sliced cornu cervi, adding deionized water for heating and stirring, centrifuging, and discarding the precipitate so as to obtain the sliced cornu cervi solution; and mixing and ultrasonically treating the mixed powder, the supernatant and the sliced cornu cervi solution, and stirring to dry, thereby obtaining the product. The medicine disclosed by the invention is used for treating meningitis, particularly is extremely effective on symptoms of tubercular meningitis, is fast in efficacy under the combined effects of the various raw materials, and is obvious in curative effects, high in cure rate, free of toxic or side effect, safe and effective; and the adopted raw materials are simple, the preparation process is simple, and the preparation method is low in cost and applicable to industrial production and large-scale popularization.

Description

Technical field [0001] The invention relates to the technical field of medicine, in particular to a medicine for treating meningitis and its preparation method and application. Background technique [0002] Meningitis (meningitis) refers to diffuse inflammatory changes in the pia mater. It is caused by various biological pathogenic factors such as bacteria, viruses, fungi, spirochetes, protozoa, rickettsia, tumors and leukemia invading the pia mater and spinal cord. Bacterial meningitis is a particularly serious disease that requires timely treatment. If it is not treated in time, it may die within a few hours or cause permanent brain damage. Although viral meningitis is more serious, most people can recover completely, and a few have sequelae. [0003] Among them, tuberculous meningitis is a non-suppurative inflammation of the meninges caused by Mycobacterium tuberculosis. It accounts for about 6% of systemic tuberculosis and is the most common central nervous system tuberculos...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/899A61P25/00A61P29/00A61P31/06A61K35/32
CPCA61K35/32A61K36/31A61K36/428A61K36/899A61K2236/333A61K2236/39A61K2236/53A61K2300/00
Inventor 梅梅孙华威聂晶王莹王鹤
Owner 佳木斯大学附属第一医院