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Preparation method of external compound artemisia annua and artemisia selengensis mosquito repellent liquid

A mosquito repellent liquid and compound technology, which can be used in cosmetic preparations, drug combinations, pharmaceutical formulations and other directions, can solve the problems of environmental pollution, skin allergies, and the effect of repelling mosquitoes is not ideal, and achieves low alcohol content and convenient use. , good mosquito repellent effect

Inactive Publication Date: 2017-10-20
JIANGXI SCI & TECH NORMAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, this repellent with added chemical components may cause skin allergies, has certain toxicity, pollutes the environment, etc.
[0004] In recent years, there are also research reports on the use of plant extracts as mosquito repellents for humans, such as: wild chrysanthemum, geranium oil, honeysuckle oil, artemisia annua oil, nepeta oil, litsea grass oil, rosin oil, wintergreen oil, lemongrass oil, lemon eucalyptus oil, citronella oil, lavender oil, clove oil, etc., but these mosquito repellents with plant volatile oil as the main component have a short action time, generally 1-2 hours, and a single plant essential oil repels mosquitoes The effect is not ideal

Method used

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Experimental program
Comparison scheme
Effect test

preparation example Construction

[0010] A method for preparing compound double-artemisia mosquito repellent liquid for external use, which is characterized in that it comprises the following steps: 1. Preparation of ethanol solution A of Artemisia annua and Artemisia annua: Mix the buds and leaves of dried Artemisia annua with a mass ratio of 5:1 and dried Artemisia annua The leaves are crushed and placed in a reactor, and edible ethanol with a concentration of 95% and 6 times the weight of the two is added, stirred intermittently for 24 hours at room temperature, and then filtered to remove insoluble matter to obtain filtrate A for subsequent use; 2. Preparation of chamomile solution B: dry Chamomile is crushed and placed in a reactor, 8 times the weight of edible ethanol with a concentration of 95% is added, refluxed at 80°C for 6 hours, and then filtered to remove insoluble matter to obtain filtrate B, which is set aside;

[0011] 3. Preparation of double Artemisia mosquito repellent: add the raw materials ...

Embodiment 1

[0013] Specific ratio: filtrate A: 30%, filtrate B: 2%, lemon eucalyptus oil 1.5%, p-menthyl-3,8-diol (PMD) 11%, menthol 1.2%, PEG-40 hydrogenated castor oil The solubilizer is 5%, the balance is deionized water, and the sum of each component is 100%. Example 2:

Embodiment 2

[0014] Specific ratio: filtrate A: 38%, filtrate B: 6%, lemon eucalyptus oil 1%, p-menthyl-3,8-diol (PMD) 14%, menthol 1.5%, PEG-40 hydrogenated castor oil The solubilizer is 2.5%, the balance is deionized water, and the sum of each component is 100%.

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Abstract

The invention relates to a preparation method of external compound artemisia annua and artemisia selengensis mosquito repellent liquid. The method comprises the following steps that artemisia annua flower buds, branches and leaves and artemisia selengensis leaves are smashed and put into a reactor; edible alcohol is added for stirring; filtering is performed to obtain filter liquid A; chamomiles are smashed; the edible alcohol is added for backflow; filtering is performed to obtain filtering liquid B; the following raw materials (in percentage by volume) including 30 to 40 percent of filter liquid A, 2 to 10 percent of filter liquid B, 1 to 2 percent of eucalyptus citriodora oil, 10 to 15 percent of p-menthyl-3,8-diol, 1 to 2 percent of menthol, 0.5 to 5 percent of PEG-40 hydrogenated castor oil solubilizing agents and the balance of water are sequentially added into the reactor; stirring is performed for uniform mixing; still standing, filtering and filling are performed; the mosquito repellent liquid is obtained. The mosquito repellent liquid has the following advantages that green and environment-friendly effects are achieved; safety and no toxicity are realized; a good mosquito repellent effect is achieved; the mosquito repellent retention time is longer than 4h; in the use process, the mosquito repellent liquid can be directly smeared or sprayed onto the human skin, has the effects of in vitro bacteriostasis, plasmodium resistance, itching relieving, skin comfort and the like are achieved and has no side effect on the human body; the use is convenient.

Description

technical field [0001] The invention relates to a mosquito repellent preparation, in particular to a method for preparing an external compound double wormwood repellent liquid. Background technique [0002] Mosquitoes suck human blood, spread diseases, seriously endanger human health and affect people's daily life. People have been looking for ways to repel and kill mosquitoes, and various chemically synthesized insecticides have also been born, but organically synthesized insecticides also left many problems such as drug resistance and affecting ecological balance. Artemisia annua (Artemisia annua L. ), Artemisia annua ( Artemisia Selengensis Turcz ) is a plant belonging to the genus Artemisia in the family Asteraceae, and the various biologically active ingredients it contains have antimalarial, antibacterial, antioxidative, mosquito repellent, and insecticidal effects. Lemon eucalyptus oil is extracted from eucalyptus leaves, and is used in medicine to prepare cough...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/9789A61K8/92A61Q17/02A61Q17/00A61P31/02A61P17/04A61P33/06
CPCA61K8/922A61K8/97A61Q17/005A61Q17/02Y02A50/30
Inventor 肖伟洪肖强利冬元丁海新肖雪
Owner JIANGXI SCI & TECH NORMAL UNIV