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A composition capable of preventing and controlling hyperlipidemia and its resulting cardiovascular and cerebrovascular or neuron damage, and corresponding preparation and use methods

A neuron injury, cardiovascular and cerebrovascular technology, applied in the field of medicine, can solve the problems of heavy economic burden, high price of lycopene, etc., achieve the effect of neuron prevention, easy daily use, and reduce drug side effects

Active Publication Date: 2020-02-11
CENT SOUTH UNIV
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Our long-term preliminary research shows that lycopene has strong antioxidant capacity and can play a positive protective role on cardiovascular and cerebrovascular, neurons, and liver. However, for the human body, in order to achieve the desired effect, it needs to consume Large doses of lycopene, the dose exceeds the tolerable maximum intake recommended in the "Chinese Residents' Dietary Nutrient Reference Intakes (2013 Edition)", and the price of lycopene is relatively expensive, if long-term higher doses of pure Taking lycopene may bring heavy economic burden to users

Method used

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  • A composition capable of preventing and controlling hyperlipidemia and its resulting cardiovascular and cerebrovascular or neuron damage, and corresponding preparation and use methods
  • A composition capable of preventing and controlling hyperlipidemia and its resulting cardiovascular and cerebrovascular or neuron damage, and corresponding preparation and use methods
  • A composition capable of preventing and controlling hyperlipidemia and its resulting cardiovascular and cerebrovascular or neuron damage, and corresponding preparation and use methods

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Embodiment

[0031] A composition of the present invention capable of preventing and controlling hyperlipidemia and the resulting cardiovascular and cerebrovascular or neuronal damage, comprising the following main components in parts by mass: 10-40 parts of lycopene, 100 parts of vitamin C and fluorine 5-20 parts of vastatin sodium, and the following auxiliary materials in parts by mass: 30-50 parts of pregelatinized starch, 1-3 parts of crospovidone and 0.1-0.3 parts of micronized silica gel. The lycopene, vitamins and fluvastatin sodium in the composition are all in powder form of 10-100 mesh; the composition can be made into a capsule preparation, and the capsule shell used in the capsule preparation is a light-shielding enteric-coated hollow capsule shell . The preparation method is as follows: under the condition of avoiding light, accurately weigh the dried fluvastatin sodium powder, vitamin C powder (unoxidized white powder), lycopene powder and the above-mentioned auxiliary materi...

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Abstract

The invention provides a composite capable of preventing and controlling hyperlipidemia and heart vessel, cerebral vessel or neuron damage caused by the hyperlipidemia. The composite mainly comprises the following components in parts by mass: 10-40 parts of lycopene, 100 parts of vitamin C and 5-20 parts of fluvastatin sodium. The invention further provides a preparation method and a use method of the composite. The composite combines the low-dose lycopene, low-dose fluvastatin sodium and the certain-dose vitamin C for the first time based on an effect of the lycopene for efficiently preventing the hyperlipidemia from damaging a heart vessel, a cerebral vessel and a neuron and by virtue of an idea of system biology, so that synergetic effects of reducing blood fat, protecting the heart vessel, the cerebral vessel and the neuron and preventing non-infective chronic diseases are exerted; the dose of statins and the lycopene is reduced; toxic and side effects of a medicine are reduced; the cost of the medicine is lowered; and the composite has good economic and social benefits.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a composition capable of preventing and controlling hyperlipidemia and the damage to cardiovascular and cerebrovascular or neurons caused by it, and corresponding preparation and use methods. Background technique [0002] Dyslipidemia usually refers to elevated serum cholesterol (TC) and / or triglyceride (TG) levels, commonly known as hyperlipidemia. In fact, dyslipidemia also generally refers to various blood lipid abnormalities including low high-density lipoproteinemia. Hyperlipidemia can cause lipid metabolism disorder to damage brain tissue, and chronic metabolic diseases of the brain, Smith–Lemli–Opitz syndrome, Huntington’s, Alzheimer’s Alzheimer's, Niemann–Pick Type C diseases and other diseases are related, and are also risk factors for stroke, coronary heart disease, myocardial infarction, hypertension, and diabetes. [0003] Elevated blood cholesterol (TC...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/405A61K31/375A61K31/01A61K9/48A61P3/06A61P9/00A61P25/00
CPCA61K9/4808A61K31/01A61K31/375A61K31/405A61K2300/00
Inventor 胡敏予申子宜杨玮春张建芬史鹤
Owner CENT SOUTH UNIV
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