Anti-caries toothpaste containing American cockroach extract

A technology of Periplaneta americana and its extracts, applied in medical preparations containing active ingredients, dentistry, drug combinations, etc., to achieve the effects of reducing tartar, improving dental caries, preventing and terminating dental caries

Inactive Publication Date: 2017-11-24
李映波 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, fluoride also has some shortcomings, especially in areas with high fluori

Method used

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  • Anti-caries toothpaste containing American cockroach extract
  • Anti-caries toothpaste containing American cockroach extract
  • Anti-caries toothpaste containing American cockroach extract

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0044] Prepare materials according to the following mass ratios:

[0045]Calcium pyrophosphate 30.0%, Silicon dioxide 15.0%, Glycerin 10.0%, Sorbitol 10.0%, Carmellose sodium 1.0%, PVM / MA copolymer 1.0%, Xylitol 2.0%, Lauryl sulfate Sodium 1.5%, Sodium Lauroyl Sarcosinate 1.5%, Sodium Benzoate 0.02%, Sodium Monofluorophosphate 0.76%, Hydroxyapatite 5.0%, Gallnut Extract 1.0%, Periplaneta Americana Extract 1.0%, Fragrance 0.3%, Deionized water 19.92%;

[0046] Go through the following steps:

[0047] 1). Add sodium carboxymethyl cellulose, PVM / MA copolymer, glycerin and sorbitol to the glue pot in turn, homogeneously disperse evenly, immediately add deionized water and mix evenly, heat to 80°C and keep for 20min to make the glue fully expand, and then cool to a temperature lower than 40°C to obtain a mixed solution;

[0048] 2). Transfer the mixed solution in step 1) to the paste making machine, and add xylitol, sodium benzoate, sodium monofluorophosphate, gallnut extract, s...

Embodiment 2

[0052] Prepare materials according to the following mass ratios:

[0053] Calcium Pyrophosphate 40.0%, Silicon Dioxide 10.0%, Glycerin 15.0%, Sorbitol 15.0%, Sodium Carboxymethylcellulose 1.0%, PVM / MA Copolymer 1.0%, Xylitol 2.0%, Lauryl Sulfate Sodium 1.0%, Sodium Lauroyl Sarcosinate 1.0%, Sodium Benzoate 0.02%, Sodium Monofluorophosphate 0.55%, Hydroxyapatite 1.0%, Gallnut Extract 1.0%, Periplaneta Americana Extract 1.2%, Fragrance 0.3%, Deionized water 9.93%;

[0054] Go through the following steps:

[0055] 1). Add sodium carboxymethyl cellulose, PVM / MA copolymer, glycerin and sorbitol to the glue pot in turn, and disperse evenly. Immediately add deionized water and mix evenly. Heat to 85°C for 15 minutes to make the glue fully expand, and then cool to a temperature lower than 40°C to obtain a mixed solution;

[0056] 2). Transfer the mixed solution in step 1) to the paste making machine, and add xylitol, sodium benzoate, sodium monofluorophosphate, gallnut extract, sod...

Embodiment 3

[0060] Prepare materials according to the following mass ratios:

[0061] Calcium pyrophosphate 35.0%, silicon dioxide 8.75%, glycerin 12.0%, sorbitol 12.0%, sodium carboxymethylcellulose 0.7%, PVM / MA copolymer 0.7%, xylitol 2.2%, lauryl sulfate Sodium 1.25%, Sodium Lauroyl Sarcosinate 1.25%, Sodium Benzoate 0.02%, Sodium Monofluorophosphate 0.3%, Hydroxyapatite 2.0%, Gallnut Extract 1.0%, Periplaneta Americana Extract 1.5%, Fragrance 0.3%, Deionized water 21.03%;

[0062] Go through the following steps:

[0063] 1). Add sodium carboxymethyl cellulose, PVM / MA copolymer, glycerin and sorbitol to the glue pot in turn, and disperse evenly. Immediately add deionized water and mix evenly. Heat to 90°C for 10 minutes to make the glue fully expand, and then cool to a temperature lower than 40°C to obtain a mixed solution;

[0064] 2). Transfer the mixed solution in step 1) to the paste making machine, and add xylitol, sodium benzoate, sodium monofluorophosphate, gallnut extract, s...

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Abstract

The invention provides an anti-caries toothpaste containing an American cockroach extract. The toothpaste is characterized by being prepared from the following raw materials in percentage by weight: 40.0 to 55.0% of abrasive agent, 18.0 to 33.0% of excipient, 1.0 to 2.0% of glue, 0 to 5.0% of xylitol, 2.0 to 4.0% of foaming agent, 0.02% of sodium benzoate, 0 to 0.3% of essence, 0 to 0.76% of sodium monofluorophosphate, 0 to 5.0% of hydroxyl apatite, 1.0% of Chinese gall extract, 0.5 to 3.0% of American cockroach extract, and the balance being deionized water, wherein the total percentage of all components is 100%. The toothpaste contains the American cockroach extract and Chinese gall extract, and thus has a very good effect on preventing and curing caries, reducing tooth tartar, relieving pain, and killing bacteria.

Description

technical field [0001] The invention relates to a toothpaste, in particular to an anti-caries toothpaste containing an extract of Periplaneta americana, and belongs to the technical field of oral care products and production methods thereof. Background technique [0002] Caries, commonly known as tooth decay, is a progressive lesion of the hard tissue of the tooth. It is manifested as demineralization of inorganic matter and decomposition of organic matter. The currently accepted theory of caries etiology is the quadruple factor theory, which mainly includes bacteria, oral environment, host and time. The mechanism of production is: cariogenic food sugar (especially sucrose and refined carbohydrates) is tightly attached to the tooth surface, and an acquired film is formed by salivary protein. This film can be firmly attached to the tooth surface, and at a suitable temperature, the bacteria in the deep layer of the plaque will produce acid within a sufficient time, attack th...

Claims

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Application Information

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IPC IPC(8): A61K8/98A61K35/64A61Q11/00A61P1/02A61P29/00A61P31/02
CPCA61K8/987A61K35/63A61K2800/28A61Q11/00A61K2300/00
Inventor 李映波黎静孙笠雯赵思聪
Owner 李映波
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