Multivitamin and mineral effervescent tablet for children and adolescents and preparation method thereof
A technology for vitamins and teenagers, which is applied in drug combination, drug delivery, and pharmaceutical formulations. It can solve problems affecting nutritional supplements, consumers are difficult to comply, and mentally immature. cost effect
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[0065] According to another aspect of the present invention, the present invention also provides a preparation method for the above-mentioned multivitamin and mineral effervescent tablet for children and adolescents, comprising the following steps:
[0066] (a) uniformly mixing vitamin A, folic acid, vitamin C, acid agent, sweetener, filler, binder and optional essence and acid agent, wet granulation and drying to obtain the first granule;
[0067] (b) Vitamin B 1 , Vitamin B 2 , Vitamin B 6 , sodium selenite, zinc oxide, ferrous gluconate, calcium lactate, calcium carbonate, alkali agent and binder are mixed uniformly, wet granulated and dried to obtain the second granule;
[0068] (c) uniformly mixing the first granule and the second granule, and compressing into tablets, to obtain effervescent tablets of multivitamins and minerals for children and adolescents.
[0069] The preparation method of the multi-vitamin and mineral effervescent tablet for children and adolescent...
Embodiment 1
[0083] This embodiment provides a kind of multi-vitamin mineral effervescent tablet for children and teenagers, which is prepared from the following raw materials in parts by mass: main ingredients: 29000 parts of calcium carbonate, 56000 parts of calcium lactate, 350 parts of zinc oxide , vitamin A 150 parts, vitamin C 1800 parts, ferrous gluconate 2700 parts, vitamin B 1 15 servings, vitamin B 2 25 servings, vitamin B 6 15 parts, 6 parts of folic acid, 10 parts of sodium selenite; excipients: 140679 parts of citric acid, 110000 parts of sodium bicarbonate, 650 parts of povidone K30, 3500 parts of maltodextrin, 500 parts of sucralose, 4600 parts of lactose.
Embodiment 2
[0085] This embodiment provides a kind of multivitamin mineral effervescent tablet for children and adolescents, which is prepared from the following raw materials in parts by mass: main ingredients: 31000 parts of calcium carbonate, 54000 parts of calcium lactate, 400 parts of zinc oxide , vitamin A 100 parts, vitamin C 1900 parts, ferrous gluconate 2500 parts, vitamin B 1 25 servings, vitamin B 2 15 servings, vitamin B 6 20 parts, 4 parts of folic acid, 15 parts of sodium selenite; excipients: 143000 parts of citric acid, 107571 parts of sodium bicarbonate, 550 parts of povidone K30, 3700 parts of maltodextrin, 510 parts of sucralose, 4690 parts of lactose.
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Abstract
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