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Medicine composition for treating gynecological inflammation, and application, kit and package part

A technology for gynecological inflammation and a kit, which is applied in the field of pharmaceutical compositions for gynecological inflammation, can solve the problems of long-term use of suppositories, inconvenience of long-term use, slow onset of effect, and long cycle, and achieve excellent therapeutic effects and less toxic and side effects.

Active Publication Date: 2018-01-19
GUIZHOU RUIHE PHARMA CO LTD LONGLI PHARMA FACTORY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, single use of certain products, especially traditional Chinese medicine oral products, has a slow onset of action and a long cycle, and the irritation of suppositories and other products is not suitable for long-term use. Currently, the health care effect of lotion and the like is more than therapeutic effect, so a reasonable drug combination plan is needed to improve the situation

Method used

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  • Medicine composition for treating gynecological inflammation, and application, kit and package part
  • Medicine composition for treating gynecological inflammation, and application, kit and package part
  • Medicine composition for treating gynecological inflammation, and application, kit and package part

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] The pharmaceutical composition preparation that embodiment 1 hemorrhoids and Shuanghuangxiaoyan make

[0029] Prescription: Honeysuckle 264g, Sophora flavescens 188g, Phellodendron 33g, Galla 99g, Cnidium 133g, Sweet potato vine 133g; Three needles 191g, Scutellaria baicalensis 64g

[0030]Preparation method: honeysuckle vine, flavescens, Phellodendron cortex, gallnut, cnidium, sweet potato vine six flavors, soak in water for 2 hours, decoct three times (8 times the amount of water each time), the first time for 3 hours, the second time for 2 hours, For the third time, 1 hour, the decoction was combined, filtered, and the filtrate was concentrated into a clear ointment with a relative density of 1.12-1.16 (80°C) to obtain Zhiji Qing ointment for later use; Scutellaria baicalensis was decocted three times with 8, 6, and 6 times the amount of water respectively. , 3 hours for the first time, 1 hour for the second time, 0.5 hours for the third time, combine the decoction, ...

Embodiment 2

[0033] The hemorrhoid preparation and the Shuanghuang anti-inflammatory preparation are made into kits / packages

[0034] preparation of formulations

[0035] Hemorrhoids lotion: 1000ml of lotion was prepared according to the quality standard WS-10496 (ZD-0496)-2002-2012Z, and the prescription: 264g of honeysuckle, 188g of sophora, 33g of Phellodendron chinensis, 99g of Galla gall, 133g of Cnidium chinensis, and 133g of sweet potato vine; Specifications: 20ml / bottle, 100ml / bottle. The crude drug content is 0.85g / ml.

[0036] Shuanghuang Xiaoyan Tablets: according to the quality standard WS 3 -B-0235-90-6 prepared 1000 tablets, of which prescription: three needles 1286g, baicalin 429g; specifications: 6 tablets / board, 12 tablets / board. Crude drug content: 1.7g / tablet.

[0037] Shuanghuang Xiaoyan Capsules: 1000 capsules prepared according to the quality standard YBZ09012006-2009Z, of which prescription: three needles 1286g, Scutellaria baicalensis 429; specifications: 6 cap...

experiment example 1

[0043] Experimental Example 1 Comparative observation of the anti-inflammatory, antibacterial and antipruritic effects of hemorrhoids combined with Shuanghuang Xiaoyan on experimental mice

[0044] 1.1 Materials

[0045] 1.1.1 Animals: Experimental animals: female Kunming mice, weighing 20-30g.

[0046] 1.1.2 Drug grouping and administration:

[0047] Experimental group 1: the pharmaceutical composition of hemorrhoids and Shuanghuang anti-inflammatory, prepared according to the method of Example 1, the crude drug content is 1.1g / ml; the clinical daily dosage for adults is 40ml, that is, 44g crude drug.

[0048] Experiment 2 groups: the test kit / package of hemorrhoid lotion+Shuanghuang Xiaoyan Tablets, prepared according to the method in Example 2, divided into: experiment 2-1 (hemorrhoids: 40ml is 34g crude drug, Shuanghuang Anti-inflammatory: 6 capsules or 10.2g crude drug), experiment 2-2 (hemorrhoid: 35ml or 29.75g crude drug, Shuanghuang anti-inflammatory: 4 capsules or ...

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Abstract

The invention relates to a medicine composition for treating gynecological inflammation, and application, a kit and a package part. The medicine composition, the kit and the package part contain haemorrhoid washing solutions with an effective treatment amount and Shuanghuang anti-inflammation tablets with an effective treatment amount which are used as joint preparations for simultaneous, separateor sequential use. When the medicine composition, the kit and the package part are used for treating elytritis, cervicitis, abnormal leucorrhea and vaginal itching, the excellent treatment effect isobtained, and the toxic or side effect is little.

Description

technical field [0001] The invention relates to a pharmaceutical composition for gynecological inflammation, in particular to a pharmaceutical composition and application for gynecological inflammation. Background technique [0002] Diseases of the female reproductive system are gynecological diseases, including vulvar diseases, vaginal diseases, uterine diseases, fallopian tube diseases, ovarian diseases, etc. Gynecological diseases are common and frequently-occurring diseases of women. Among them, especially gynecological inflammation has the highest incidence rate, such as vaginitis, cervicitis, abnormal leucorrhea, genital itching, etc., which bring troubles to women's daily life. At present, methods such as oral medicine, suppository administration or lotion washing and fumigation are mainly used for the treatment of gynecological inflammation and private parts care. At present, the commonly used lotions on the market include Fuyanjie, Jieeryin and other lotions, as w...

Claims

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Application Information

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IPC IPC(8): A61K36/756A61P15/02A61P15/00A61P17/04A61K35/64
Inventor 薛捷张禄权田紫平庞雨先德清杨方炳
Owner GUIZHOU RUIHE PHARMA CO LTD LONGLI PHARMA FACTORY
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